Effect of local background intensities in the normalization of cDNA microarray data with a skewed expression profiles

Experimental and Molecular Medicine

Volumn 34, Issue 3, 2002, Pages 224-232

  Kim, Jin Hyuk ^a   Shin, Dong Mi ^a   Lee, Yong Sung ^a  

^a Hanyang University   (South Korea)

Author keywords

Background; cDNA microarray; LOWESS; Normalization; Printing pin

Indexed keywords

COMPLEMENTARY DNA; CARBOCYANINE; CYANINE DYE 3; CYANINE DYE 5;

ARTICLE; DNA MICROARRAY; GENE EXPRESSION; IMAGE ANALYSIS; NOISE; SIGNAL NOISE RATIO; SIGNAL PROCESSING; GENE EXPRESSION PROFILING; GENETICS; METHODOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STANDARD; STATISTICAL MODEL;

CARBOCYANINES; DNA, COMPLEMENTARY; GENE EXPRESSION PROFILING; LINEAR MODELS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0037205962     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2002.31     Document Type: Article

References (6)

1. Ratio-based decisions and quantitative analysis of cDNA microarray images
2. Analysis of variance for gene expression microarray data
3. A novel method using edge detection for signal extraction from cDNA microarray image analysis
4. A statistical method for flagging weak spots improves normalization and ratio estimates in microarrays
5. Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation