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Volumn 124, Issue 30, 2002, Pages 8825-8833
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Computer simulations of trypanosomal nucleoside hydrolase: Determination of the protonation state of the bound transition-state analogue
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Author keywords
[No Author keywords available]
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Indexed keywords
KINETIC ISOTOPE EFFECTS;
BIOSYNTHESIS;
COMPUTER SIMULATION;
HYDROGEN BONDS;
HYDROLYSIS;
MOLECULAR DYNAMICS;
NUCLEIC ACIDS;
ENZYMES;
4 AMINOPHENYLIMINORIBITOL;
INOSINE DERIVATIVE;
NUCLEOSIDASE;
UNCLASSIFIED DRUG;
AB INITIO CALCULATION;
ARTICLE;
CONFORMATION;
CRYSTAL STRUCTURE;
ENZYME ACTIVE SITE;
ENZYME ANALYSIS;
GEOMETRY;
HYDROGEN BOND;
HYDROLYSIS;
HYDROPHOBICITY;
MOLECULAR DYNAMICS;
PROTON TRANSPORT;
TRYPANOSOMA;
ANIMALS;
BINDING SITES;
COMPUTER SIMULATION;
CRITHIDIA FASCICULATA;
CRYSTALLOGRAPHY, X-RAY;
ENZYME INHIBITORS;
MODELS, CHEMICAL;
MODELS, MOLECULAR;
N-GLYCOSYL HYDROLASES;
PROTEIN CONFORMATION;
RIBITOL;
STEREOISOMERISM;
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EID: 0037205913
PISSN: 00027863
EISSN: None
Source Type: Journal
DOI: 10.1021/ja020312x Document Type: Article |
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Times cited : (21)
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References (28)
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