Synthesis and evaluation of iron chelators with masked hydrophilic moieties

Journal of the American Chemical Society

Volumn 124, Issue 43, 2002, Pages 12666-12667

  Meijler, Michael M ^a   Arad Yellin, Rina ^a   Cabantchik, Z Ioav ^b   Shanzer, Abraham ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CHELATING AGENT; DEFEROXAMINE; FERRICHROME; IRON CHELATE; SIDEROPHORE;

ARTICLE; CHELATION; FLUORESCENCE; HYDROLYSIS; HYDROPHILICITY; IRON OVERLOAD; IRON TRANSPORT; OXIDATIVE STRESS; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0037202135     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja027013s     Document Type: Article

References (11)

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11. Murine erythroleukemia cells were incubated with compounds 4 and 5 (100 μM) for 60 min at 37 °C in PBS (pH 7.4) and centrifuged at 3000 rpm for 2 min. After being washed in PBS, the cells were centrifuged again and resuspended in PBS, and the fluorescence (excitation and emission at 400 and 530 nm, respectively) was measured. After another 60 min, the cells were centrifuged and resuspended in PBS, and the fluorescence was measured again.