Lithium and proton templated ω-polyazamacrolactamization, new general routes to macrocyclic polyamines

Tetrahedron Letters

Volumn 43, Issue 40, 2002, Pages 7213-7216

  Drandarov, Konstantin ^a   Hesse, Manfred ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Lithium template; Polyazamacrolactam alkaloids; Proton template; Spermidine; Spermine

Indexed keywords

ALKALOID DERIVATIVE; LITHIUM; MACROCYCLIC COMPOUND; POLYAMINE DERIVATIVE; PROTON; SPERMIDINE; SPERMINE;

ARTICLE; CATALYST; SYNTHESIS;

EID: 0037201154     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01660-X     Document Type: Article

References (26)

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22. + in MeOH.
23. --form (strong anionite, Fluka), corresponding to 10-fold excess of exchange capacity, then filtered and evaporated.
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26. The present method was successfully used in our laboratory also for the preparation of a group of compounds similar to the polyazamacrolactams shown here (Yurdakul, A. et al. in preparation).