The antinociceptive effect of mirtazapine in mice is mediated through serotonergic, noradrenergic and opioid mechanisms

Brain Research Bulletin

Volumn 58, Issue 6, 2002, Pages 601-605

  Schreiber, Shaul ^a   Rigai, Tova ^b   Katz, Yeshayahu ^c,d   Pick, Chaim G ^b  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^d HAEMEK MEDICAL CENTER   (Israel)

Author keywords

Antidepressants; Antinociception; Hotplate; Mirtazapine; Noradrenaline; Opioid receptor subtypes; Pain; Serotonin

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; ADRENERGIC RECEPTOR; ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR; BETA FUNALTREXAMINE; CLONIDINE; DELTA OPIATE RECEPTOR; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; KAPPA OPIATE RECEPTOR; METERGOLINE; MIRTAZAPINE; MORPHINE; NALORPHINE; NALOXONAZINE; NALOXONE; NALTRINDOLE; NORBINALTORPHIMINE; OPIATE RECEPTOR; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; YOHIMBINE;

ANALYZER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; HOT PLATE TEST; MALE; MOUSE; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM;

ADRENERGIC AGONISTS; ADRENERGIC ANTAGONISTS; ANALGESICS; ANALGESICS, OPIOID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; MALE; MIANSERIN; MICE; MICE, INBRED ICR; NARCOTIC ANTAGONISTS; PAIN MEASUREMENT; RECEPTORS, OPIOID; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0037201092     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(02)00825-0     Document Type: Article

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