Norepinephrine elicits β2-receptor-mediated dilation of isolated human coronary arterioles

Circulation

Volumn 106, Issue 5, 2002, Pages 550-555

  Sun, Dong ^a   Huang, An ^a   Mital, Seema ^a   Kichuk, Maryanne R ^a   Marboe, Charles C ^a   Addonizio, Linda J ^a   Michler, Robert E ^a   Koller, Akos ^a   Hintze, Thomas H ^a   Kaley, Gabor ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Arteries; Norepinephrine; Receptors, adrenergic

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BUTOXAMINE; METHOXAMINE; N(G) NITROARGININE; NORADRENALIN; PRACTOLOL; PRAZOSIN; PROPRANOLOL; THROMBOXANE DERIVATIVE; U 44619; UNCLASSIFIED DRUG; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ENZYME INHIBITOR; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

ADOLESCENT; ADULT; ARTERIOLE; ARTERY CONSTRICTION; ARTERY DILATATION; ARTICLE; CANNULATION; CHILD; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; DOSE RESPONSE; ENDOTHELIUM; FEMALE; HEART LEFT VENTRICLE; HUMAN; HUMAN TISSUE; INFANT; MALE; PRIORITY JOURNAL; SMOOTH MUSCLE; CORONARY BLOOD VESSEL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; HEART DISEASE; IN VITRO STUDY; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PRESCHOOL CHILD; VASCULAR ENDOTHELIUM; VASCULAR PATENCY; VASODILATATION;

ADOLESCENT; ADRENERGIC ALPHA-AGONISTS; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ADULT; ARTERIOLES; CHILD; CHILD, PRESCHOOL; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FEMALE; HEART DISEASES; HUMANS; INFANT; MALE; MIDDLE AGED; NOREPINEPHRINE; RECEPTORS, ADRENERGIC, BETA-2; VASCULAR PATENCY; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 0037199258     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000023896.70583.9F     Document Type: Article

References (36)

1. Reduced NO-dependent arteriolar dilation during the development of cardiomyopathy
2. Endothelium-dependent dilation of the coronary microvasculature is impaired in dilated cardiomyopathy
3. Acetylcholine causes coronary vasodilation in dogs and baboons
4. The effect of norepinephrine on the coronary microcirculation
5. Pharmacologic activation of the human coronary microcirculation in vitro: Endothelium-dependent dilation and differential responses to acetylcholine
6. Responses of coronary smooth muscle to catecholamines
7. Control of myocardial oxygen tension by sympathetic coronary vasoconstriction in the dog
8. α-adrenoceptor attenuation of the coronary vascular response to severe exercise in the conscious dog
9. 2-adrenergic receptors in the coronary microcirculation
10. Heterogeneous microvascular coronary α-adrenergic vasoconstriction
11. 1-adrenergic responses of isolated canine coronary microvessels
12. Adrenergic vasomotion in the coronary microcirculation
13. Beta-receptor subtypes in the canine coronary circulation
14. Feedforward control of coronary blood flow via coronary β-receptor stimulation
15. α-adrenergic coronary vasoconstriction and myocardial ischemia in humans
16. 1-adrenergic constriction
17. Neural control of coronary blood flow
18. The alpha adrenoceptors on endothelial cells
19. Alpha-2 adrenoreceptors and endothelium-dependent relaxation in canine large arteries
20. 2-adrenergic constriction in the canine epicardial coronary microcirculation
21. Lack of importance of NO in β-adrenoceptor-mediated relaxation of large epicardial canine coronary arteries
22. ATP channels and nitric oxide in conscious dogs
23. β-adrenoceptors on endothelial cells do not influence release of relaxing factor in dog coronary arteries
24. Coronary β-adrenoceptor function is modified by the endothelium in heart failure
25. New views of human cardiac β-adrenoceptors
26. Effects of adrenoceptor activators and inhibitors on the coronary circulation
27. Isolated human coronary arteries in response to vasoconstrictor substances
28. 2-adrenoceptors
29. Adventitia-dependent influences on vascular function
30. Inhibition of adrenergic vasoconstriction by endothelial cell shear stress
31. Inhibition of nitric oxide synthesis augments centrally induced sympathetic coronary vasoconstriction in cats
32. Regulation of nitric oxide production in human coronary microvessels and the contribution of local kinin formation
33. Potentiation of coronary vasoconstriction by beta-adrenergic blockade in patients with coronary artery disease
34. Reflex increase in coronary vascular resistance in patients with ischemic heart disease
35. Feedforward sympathetic coronary vasodilation in exercising dogs
36. Quantitative analysis of feedforward sympathetic coronary vasodilation in exercising dogs