Anisotropic conduction properties in canine atria analyzed by high-resolution optical mapping: Preferential direction of conduction block changes from longitudinal to transverse with increasing age

Circulation

Volumn 105, Issue 17, 2002, Pages 2092-2098

  Koura, Takahiro ^a   Hara, Motoki ^a   Takeuchi, Susumu ^b   Ota, Kenichi ^a   Okada, Yasumasa ^c   Miyoshi, Shunichiro ^a   Watanabe, Atsushi ^d   Shiraiwa, Kazumi ^d   Mitamura, Hideo ^a   Kodama, Itsuo ^b   Ogawa, Satoshi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d ASAHI KASEI CORPORATION   (Japan)

Author keywords

Anisotropy; Atrium; Conduction; Gap junctions

Indexed keywords

AGING; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANISOTROPY; ARTICLE; CONTROLLED STUDY; DOG; HEART ARRHYTHMIA; HEART ATRIUM CONDUCTION; HEART BLOCK; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MUSCLE FIBRIL; NONHUMAN; PRIORITY JOURNAL;

ACTION POTENTIALS; AGING; ANIMALS; ANISOTROPY; ATRIAL FUNCTION; BODY SURFACE POTENTIAL MAPPING; CARDIAC PACING, ARTIFICIAL; CONNEXIN 43; CULTURE TECHNIQUES; DOGS; ELECTRIC CONDUCTIVITY; GAP JUNCTIONS; HEART ATRIA; HEART BLOCK; IMMUNOHISTOCHEMISTRY; KINETICS; MICROSCOPY, FLUORESCENCE; SENSITIVITY AND SPECIFICITY;

EID: 0037197724     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000015506.36371.0D     Document Type: Article

References (18)

1. Influence of passive anisotropic properties on directional differences in propagation following modification of the sodium conductance in human atrial muscle: A model of reentry based on anisotropic discontinuous propagation
2. Relating extracellular potentials and their derivatives to anisotropic propagation at a microscopic level in human cardiac muscle: Evidence for electrical uncoupling of side-to-side fiber connections with increasing age
3. The functional role of structural complexities in the propagation of depolarization in the atrium of the dog: Cardiac conduction disturbances due to discontinuities of effective axial resistivity
4. The discontinuous nature of propagation in normal canine cardiac muscle: Evidence for recurrent discontinuities of intracellular resistance that affect the membrane currents
5. Immunolabeling patterns of gap junction connexins in the developing and mature rat heart
6. Spatiotemporal relationship between gap junctions and fascia adherens junctions during postnatal development of human ventricular myocardium
7. Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of subacute canine infarcts
8. Anisotropic conduction and reentry in perfused epicardium of rabbit left ventricle
9. Determinants and mechanisms of flecainide-induced promotion of ventricular tachycardia in anesthetized dogs
10. Anisotropic conduction properties of canine ventricular muscles. Influence of high extracellular K+ concentration and stimulation frequency
11. Reentrant excitation around a fixed obstacle in uniform anisotropic ventricular myocardium
12. Effects of increasing intercellular resistance on transverse and longitudinal propagation in sheep epicardial muscle
13. Directional differences in excitability and margin of safety for propagation in sheep ventricular epicardial muscle
14. Remodeling of gap junctional coupling in hypertrophied right ventricles of rats with monocrotaline-induced pulmonary hypertension
15. Role of wavefront curvature in propagation of cardiac impulse
16. Wave-front curvature as a cause of slow conduction and block in isolated cardiac muscle
17. Effects of bipolar point and line stimulation in anisotropic rabbit epicardium: Assessment of the critical radius of curvature for longitudinal block
18. Slow conduction in the infracted human heart. 'Zigzag' course of activation