Functional characterization of the Candida albicans homologue of secretion-associated and Ras-related (Sarl) protein

Yeast

Volumn 19, Issue 5, 2002, Pages 423-428

  Jiang, Linghuo ^a   Lee, Chang Muk ^a   Shen, Shi Hsiang ^a,b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Candida albicans; cDNA; GTPase; Intron; Sar1; Yeast

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; FUNGAL PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; RECOMBINANT PROTEIN; SECRETION ASSOCIATED AND RAS RELATED PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CANDIDA ALBICANS; CONTROLLED STUDY; DNA SEQUENCE; ENDOPLASMIC RETICULUM; GENE DELETION; GENETIC COMPLEMENTATION; GOLGI COMPLEX; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN MOTIF; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BASE SEQUENCE; BLOTTING, WESTERN; CANDIDA ALBICANS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; FUNGAL PROTEINS; GENETIC COMPLEMENTATION TEST; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, FUNGAL; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

CANDIDA; CANDIDA ALBICANS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037196928     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/yea.842     Document Type: Article

References (27)

1. Cargo selection by the COPII budding machinery during export from the ER
2. Purification and characterization of SAR1p, a small GTP-binding protein required for transport vesicle formation from the endoplasmic reticulum
3. The GTPase superfamily: A conserved switch for diverse cell functions
4. Protein isoprenylation and methylation at carboxyl-terminal cysteine residues
5. Yeast-enhanced green fluorescent protein (yEGFP)a reporter of gene expression in Candida albicans
6. Putative virulence factors of Candida albicans
7. Fission yeast and a plant have functional homologues of the Sar1 and Sec12 proteins involved in ER to Golgi traffic in budding yeast
8. Isogenic strain construction and gene mapping in Candida albicans
9. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli
10. The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport
11. Degradation of humoral host defense by Candida albicans proteinase
12. The presence of a Sar1 gene family in Brassica campestris that suppresses a yeast vesicular transport mutation Sec12-1
13. COPII-cargo interactions direct protein sorting into ER-derived transport vesicles
14. Degradation of human subendothelial extracellular matrix by proteinase-secreting Candida albicans
15. A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast
16. A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus
17. Mutational analysis of the Sar1 protein, a small GTPase which is essential for vesicular transport from the endoplasmic reticulum
18. Pathogenic fungi in the 21st century
19. Isolation of Pichia pastoris genes involved in ER-to-Golgi transport
20. Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium
21. Genomewide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae
22. The frequency of integrative transformation at phase-specific genes of Candida albicans correlates with their transcriptional state
23. Isolation of a tobacco cDNA encoding Sar1 GTPase and analysis of its dominant mutations in vesicular traffic using a yeast complementation system
24. Genomic evidence for a complete sexual cycle in Candida albicans
25. Isolation and analysis of functional homologues of the secretion-related SAR1 gene of Saccharomyces cerevisiae from Aspergillus niger and Trichoderma reesei
26. Altered adherence in strains of Candida albicans harbouring null mutations in secreted aspartic proteinase genes
27. Characterization of yeast sar1 temperature-sensitive mutants, which are defective in protein transport from the endoplasmic reticulum