Phospholipase C axis is the preferential pathway leading to PKC activation following PTH or PTHrP stimulation in human term placenta

Life Sciences

Volumn 72, Issue 2, 2002, Pages 215-225

  Laramée, Mélanie ^a   Simoneau, Lucie ^a   Lafond, Julie ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

Basal plasma membranes; Brush border membranes; PKC; Placenta; PTH; PTHrP

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BISINDOLYLMALEIMIDE; PARATHYROID HORMONE; PARATHYROID RELATED PEPTIDE; PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ARTICLE; BASEMENT MEMBRANE; BRUSH BORDER; CELL MEMBRANE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HUMAN TISSUE; PLACENTA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; CELL MEMBRANE; CHROMONES; ENZYME ACTIVATION; ENZYME INHIBITORS; ESTRENES; FEMALE; GLUCOSIDASES; HUMANS; INDOLES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALEIMIDES; MEMBRANE PROTEINS; MICROVILLI; MORPHOLINES; PARATHYROID HORMONE; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE HORMONES; PHOSPHOLIPASE C; PHOSPHOPROTEINS; PLACENTA; PREGNANCY; PROTEIN KINASE C; PYRROLIDINONES; SIGNAL TRANSDUCTION; STIMULATION, CHEMICAL; TROPHOBLASTS;

EID: 0037195592     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)02238-5     Document Type: Article

References (43)

1. Sideri M., de Virgilis G., Rainoldi R., Remotti G. The ultrastructural basis of nutritional transfer: evidence of different patterns in the plasma membranes of the multilayers placental barrier. Trophoblast Research. 1:1983;15-23.
2. Pitkin R.M. Calcium metabolism in pregnancy and perinatal period: a review. American Journal of Obstetric and Gynecology. 151:1985;99-109.
3. David L., Anast C.S. Calcium metabolism in newborn infants: the interrelationship of parathyroid function and calcium, magnesium, and phosphorus in normal, "sick ", and hypocalcemic newborns. Journal of Clinical Investigation. 54:1974;287-296.
4. Garel J.M., Barlet J.P. Calcium metabolism in newborns animals: the interrelationship of calcium, magnesium, and inorganic phosphorus in newborn rats, foals, lambs, and calves. Pediatric Research. 10:1976;749-754.
5. Rodda C.P., Kubota M., Heath J.A., Ebeling P.R., Moseley J.M., Care A.D., Caple I.W., Martin T.J. Evidence for a novel parathyroid hormone-related protein in fetal lamb parathyroid glands and sheep placenta: comparisons with a similar protein implicated in humoral hypercalcemia of malignancy. Journal of Endocrinology. 117:1988;261-271.
6. Abbas S.K., Pickard D.W., Rodda C.P., Heath J.A., Hammonds R.G., Wood W.I., Caple I.W., Martin T.J., Care A.D. Stimulation of ovine placental calcium transport by purified natural and recombinant parathyroid hormone-related protein (PTHrP) preparations. Quarterly Journal of Experimental Physiology. 74:1989;549-552.
7. Senior P.V., Heath D.A., Beck F. Expression of parathyroid hormone-related protein mRNA in the rat before birth: demonstration by hybridisation histochemistry. Journal of Molecular Endocrinology. 6:1991;281-290.
8. Care A.D., Caple I.W., Abbas S.K., Pickard D.W. The effect of fetal thyroparathyroidectomy on the transport of calcium across the ovine placenta to the fetus. Placenta. 7:1986;417-424.
9. Kovacs C.S., Lanske B., Hunzelman J.L., Guo J., Karaplis A.C., Kronenberg H.M. Parathyroid hormone-related peptide (PTHrP) regulates fetal-placental calcium transport through a receptor distinct from the PTH/PTHrP receptor. Proceedings of the National Academy of Sciences of the United states of America. 93:1996;15233-15238.
10. Rodda C.P., Caple I.W., Martin T.J. Nissenson R.A., Halloran B.P. Role of the PTHrP in fetal and neonatal physiology in Parathyroid Hormone-Related Protein: Physiology and its role in cancer. 1992;169-196 CRC Press, Boca Raton, FL.
11. Garel J.M. Distribution of labeled parathyroid hormone in rat fetus. Hormone and Metabolic Research. 4:1972;131-132.
12. Rubin L.P., Posillico J.T., Anast C.S., Brown E.M. Circulating levels of biologicaly active and immunoreactive intact parathyroid hormone in human newborns. Pediatric Research. 29:1991;201-207.
13. Chorev M., Rosenblatt M. Bilzekian J.P., Levine M.A., Marcus R. The Parathyroids. 1994;139-156 Raven, New York.
14. Jüppner H., Abou-Samra A.B., Freeman M., Kong X.F., Schipani E., Richards J., Kolawoski L.F. Jr., Hock J., Potts J.T. Jr., Kronenberg H.M. A G protein-linked receptor for parathyroid hormone and parathyroid-related-peptide. Science. 254:1991;1024-1026.
15. Matsubara S., Tamada T., Saito T. Ultracytochemical localizations of adenylate cyclase, guanylate cyclase and cyclic 3′-5′-nucleotide phosphodiesterase activity on the trophoblast in the human placenta. Direct histochemical evidence. Histochemistry. 87:1987;505-511.
16. Spiegel A.M. Role of G proteins in signal transduction. Clinical Neuropharmacology. 15:1992;200A-201A.
17. Lafond J., Auger D., Fortier J., Brunette M.G. Parathyroid hormone receptor in human placental syncytiotrophoblast brush border and basal plasma membrane. Endocrinology. 123:1988;2834-2840.
18. Lafond J., Ayotte N., Brunette M.G. Effect of (1-34) parathyroid hormone-related peptide on the composition and turnover of phospholipids in syncytiotrophoblast brush border and basal plasma membranes of human placenta. Molecular and Cellular Endocrinology. 92:1993;207-214.
19. Nishizuka Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 9:1995;484-496.
20. Kishimoto A., Takai Y., Mori T., Kikkawa U., Nishizuka Y. Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover. Journal of Biological Chemistry. 255:1980;2273-2276.
21. Abou-Samra A.B., Jüppner H., Westerberg D., Potts J.T. Jr., Segre G.V. Parathyroid hormone causes translocation of protein kinase-C from cytosol to membranes in rat osteosarcoma cells. Endocrinology. 124:1989;1107-1113.
22. Kikkawa U., Takai Y., Minakuchi R., Inohara S., Nishizuka Y. Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties. Journal of Biological Chemistry. 257:1982;13341-13348.
23. Amane A., Simoneau L., Savard R., Lafond J. Identification and chromatographic separation of protein kinase C isotypes in syncytiotrophoblast brush border membranes and basal plasma membranes of human placenta. International Journal of Biochromatography. 1:1995;237-246.
24. Ruzycky A.L., Jansson T., Illsley N.P. Differential expression of protein kinase C isoforms in the human placenta. Placenta. 17:1996;461-469.
25. Liu J.Y., Shyu J.C., Chang C.L., Tsai C.C., Chang A.C., Yang L.C., Lin L.Y., Hsieh Y.S. Protein kinase C isoforms during the development of deciduomata in pseudopregnant rats. Life Sciences. 63:1998;721-730.
26. Hruska K.A., Moskowitz D., Esbrit P., Civitelli R., Westbrook S., Huskey M. Stimulation of inositol triphosphate and diacylglycerol production in renal tubular cells by parathyroid hormone. Journal of Clinical Investigation. 79:1987;230-239.
27. Coleman D.T., Bilezikian J.P. Parathyroid hormone stimulates formation of inositol phosphates in a membrane preparation of canine renal cortical tubular cells. Journal of Bone and Mineral Research. 3:1990;299-306.
28. Siegfried G., Vrtovsnik F., Prie D., Amiel C., Friedlander G. Parathyroid hormone stimulates ecto-5′-nucleotidase activity in renal epithelial cells: role of protein kinase-C. Endocrinology. 136:1995;1267-1275.
29. Civitelli R., Martin T.J., Fausto A., Gunsten S.L., Hruska K.A., Avioli L.V. Parathyroid hormone-related peptide transiently increases cytosolic calcium in osteoblast-like cells: comparison with parathyroid hormone. Endocrinology. 125:1989;1204-1210.
30. Chakravarthy B.R., Bussey A., Whitfield J.F., Sikorska M., Williams R.E., Durkin J.P. The direct measurement of protein kinase C (PKC) activity in isolated membranes using a selective peptide substrate. Analytical Biochemistry. 196:1991;144-150.
31. Fujimori A., Cheng S., Avioli L.V., Civitelli R. Structure-function relationship of parathyroid hormone: activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells. Endocrinology. 130:1992;29-36.
32. Babich M., King K.L., Nissenson R.A. G protein-dependent activation of a phosphoinositide-specific phospholipase C in UMR-106 osteosarcoma cell membranes. Journal of Bone and Mineral Research. 4:1989;549-556.
33. Tetrin-Clary C., Chenut M.C., de la Llosa P. Isolation and characterization of protein kinase C from human placenta. Placenta. 11:1990;27-30.
34. Robidoux J., Simoneau L., St-Pierre S., Ech-Chadli H., Lafond J. Human syncytiotrophoblast NPY receptors are located on BBM and activate PLC- to -PKC axis. American Journal of Physiology. 274:1998;E502-E509.
35. Kelley M.H., Hamilton J.R. A microtechnique for assay of intestinal alkaline phosphatase. Results in normal children and children with coeliac disease. Clinical Biochemistry. 3:1970;33-43.
36. Post R.A., Sen A.K. Sodium and potassium stimulated ATPase. Methods in Enzymology. 10:1967;762-768.
37. Horiuchi N., Caulfield M.P., Fisher J.E., Goldman M.E., McKee R.L., Reagan J.E., Levy J.J., Nutt R.F., Rodan S.B., Schofield T.L., Clemens T.L., Rosenblatt M. Similarity of synthetic peptide from human tumor to parathyroid hormone in vivo and in vitro. Science. 238:1987;1566-1568.
38. Yates A.J., Gutierrez G.E., Smolens P., Travis P.S., Katz M.S., Aufdemorte T.B., Boyce B.F., Hymer T.K., Poser J.W., Mundy G.R. Effects of a synthetic peptide of a parathyroid hormone-related protein on calcium homeostasis, renal tubular calcium reabsorption, and on bone metabolism in vivo and in vitro in rodents. Journal of Clinical Investigation. 81:1988;932-938.
39. Chakravarthy B.R., Durkin J.P., Rixon R.H., Whitfield J.F. Parathyroid hormone fragment [3-34] stimulates protein kinase C (PKC) activity in rat osteosarcoma and murine T-lymphoma cells. Biochemical and Biophysical Research Communications. 171:1990;1105-1110.
40. Fukayama S., Bosma T.J., Goad D.L., Voelkel E.F., Tashjian A.H. Jr. Human parathyroid hormone (PTH)-related protein and human PTH: comparative biological activities on human bone cells and bone resorption. Endocrinology. 123:1988;2841-2848.
41. Thompson A.K., Mostafapour S.P., Denlinger L.C., Bleasdale J.E., Fisher S.K. The aminosteroid U-73122 inhibits muscarinic receptor sequestration, and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. Journal of Biological Chemistry. 266:1991;23856-23862.
42. Cosman F., Morrow B., Kopal M., Bilezikian J.P. Stimulation of inositol phosphate formation in Ros17/2.8 cell membranes by guanine nucleotide, calcium, and parathyroid hormone. Journal of Bone and Mineral Research. 4:1989;413-420.
43. Potts J.T. Jr., Jüppner H. Avioli L.V., Krane S. Metabolic bone disease. 1997;51-94 Academic Press, New York.