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Volumn 11, Issue , 2003, Pages 45-52

Discovery of molecular mechanisms of neuroprotection using cell-based bioassays and oligonucleotide arrays

Author keywords

Galanin; Oxidative stress

Indexed keywords

ANTIBIOTIC AGENT; ANTIHISTAMINIC AGENT; BROMOCRIPTINE; DITHRANOL; ERYTHROMYCIN; FLUNISOLIDE; KANAMYCIN; LITHIUM; MECLOZINE; MEGESTROL; METHAZOLAMIDE; MEXILETINE; MINOCYCLINE; NALTREXONE; NEUROPROTECTIVE AGENT; NIFEDIPINE; NIMODIPINE; NONSTEROID ANTIINFLAMMATORY AGENT; NORETHISTERONE; PRAMOCAINE; RETINOL; SCOPOLAMINE; SOTALOL; SULFACETAMIDE; SULINDAC; TIMOLOL; TRAZODONE; TROLEANDOMYCIN; UNINDEXED DRUG; VERAPAMIL; HYDROGEN PEROXIDE; OXIDIZING AGENT;

EID: 0037195201     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00064.2002     Document Type: Article
Times cited : (36)

References (62)
  • 1
    • 0030887358 scopus 로고    scopus 로고
    • Protective effect of a novel free radical scavenger, OPC-14117, on wobbler mouse motor neuron disease
    • Abe K, Morita S, Kikuchi T, and Itoyama Y. Protective effect of a novel free radical scavenger, OPC-14117, on wobbler mouse motor neuron disease. J Neurosci Res 48: 63-70, 1997.
    • (1997) J Neurosci Res , vol.48 , pp. 63-70
    • Abe, K.1    Morita, S.2    Kikuchi, T.3    Itoyama, Y.4
  • 2
    • 0035870125 scopus 로고    scopus 로고
    • Apoptotic cell debris and phosphatidylserine-containing lipid vesicles induce apolipoprotein J (clusterin) gene expression in vital fibroblasts
    • Bach UC, Baiersdorfer M, Klock G, Cattaruzza M, Post A, and Koch-Brandt C. Apoptotic cell debris and phosphatidylserine-containing lipid vesicles induce apolipoprotein J (clusterin) gene expression in vital fibroblasts. Exp Cell Res 265: 11-20, 2001.
    • (2001) Exp Cell Res , vol.265 , pp. 11-20
    • Bach, U.C.1    Baiersdorfer, M.2    Klock, G.3    Cattaruzza, M.4    Post, A.5    Koch-Brandt, C.6
  • 3
    • 0033986977 scopus 로고    scopus 로고
    • Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs
    • Barry CE III, Slayden RA, Sampson AE, and Lee RE. Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs. Biochem Pharmacol 59: 221-231, 2000.
    • (2000) Biochem Pharmacol , vol.59 , pp. 221-231
    • Barry C.E. III1    Slayden, R.A.2    Sampson, A.E.3    Lee, R.E.4
  • 4
    • 0035577767 scopus 로고    scopus 로고
    • Brain metabolism and brain disease: Is metabolic deficiency the proximate cause of Alzheimer dementia?
    • Blass JP. Brain metabolism and brain disease: is metabolic deficiency the proximate cause of Alzheimer dementia? J Neurosci Res 66: 851-856, 2001.
    • (2001) J Neurosci Res , vol.66 , pp. 851-856
    • Blass, J.P.1
  • 5
    • 0031868461 scopus 로고    scopus 로고
    • Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis
    • Bogdanov MB, Ramos LE, Xu Z, and Beal MF. Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis. J Neurochem 71: 1321-1324, 1998.
    • (1998) J Neurochem , vol.71 , pp. 1321-1324
    • Bogdanov, M.B.1    Ramos, L.E.2    Xu, Z.3    Beal, M.F.4
  • 9
    • 0035013564 scopus 로고    scopus 로고
    • Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease
    • Butterfield DA, Howard BJ, and LaFontaine MA. Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease. Curr Med Chem 8: 815-828, 2001.
    • (2001) Curr Med Chem , vol.8 , pp. 815-828
    • Butterfield, D.A.1    Howard, B.J.2    LaFontaine, M.A.3
  • 10
    • 0031807574 scopus 로고    scopus 로고
    • Megestrol acetate as a biomodulator
    • Chang AY. Megestrol acetate as a biomodulator. Semin Oncol 25: 58-61, 1998.
    • (1998) Semin Oncol , vol.25 , pp. 58-61
    • Chang, A.Y.1
  • 12
    • 0032949602 scopus 로고    scopus 로고
    • Oxidative stress and motor neurone disease
    • Cookson MR and Shaw PJ. Oxidative stress and motor neurone disease. Brain Pathol 9: 165-186, 1999.
    • (1999) Brain Pathol , vol.9 , pp. 165-186
    • Cookson, M.R.1    Shaw, P.J.2
  • 13
    • 0035213364 scopus 로고    scopus 로고
    • Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress
    • Cornelli U, Terranova R, Luca S, Cornelli M, and Alberti A. Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress. J Nutr 131: 3208-3211, 2001.
    • (2001) J Nutr , vol.131 , pp. 3208-3211
    • Cornelli, U.1    Terranova, R.2    Luca, S.3    Cornelli, M.4    Alberti, A.5
  • 16
    • 84984934048 scopus 로고    scopus 로고
    • DNA microarrays in drug discovery and development
    • Debouck C and Goodfellow PN. DNA microarrays in drug discovery and development. Nat Genet 21: 48-50, 1999.
    • (1999) Nat Genet , vol.21 , pp. 48-50
    • Debouck, C.1    Goodfellow, P.N.2
  • 19
    • 0346942394 scopus 로고    scopus 로고
    • Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays
    • Gerhold D, Lu M, Xu J, Austin C, Caskey CT, and Rushmore T. Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays. Physiol Genomics 5: 161-170, 2001.
    • (2001) Physiol Genomics , vol.5 , pp. 161-170
    • Gerhold, D.1    Lu, M.2    Xu, J.3    Austin, C.4    Caskey, C.T.5    Rushmore, T.6
  • 20
    • 2642684569 scopus 로고    scopus 로고
    • Possible neuroprotective role of clusterin in Alzheimer's disease: A quantitative immunocytochemical study
    • Giannakopoulos P, Kovari E, French LE, Viard I, Hof PR, and Bouras C. Possible neuroprotective role of clusterin in Alzheimer's disease: a quantitative immunocytochemical study. Acta Neuropathol (Berl) 95: 387-394, 1998.
    • (1998) Acta Neuropathol (Berl) , vol.95 , pp. 387-394
    • Giannakopoulos, P.1    Kovari, E.2    French, L.E.3    Viard, I.4    Hof, P.R.5    Bouras, C.6
  • 23
    • 0030050727 scopus 로고    scopus 로고
    • Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
    • Gurney ME, Cutting FB, Zhai P, Doble A, Taylor CP, Andrus PK, and Hall ED. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol 39: 147-157, 1996.
    • (1996) Ann Neurol , vol.39 , pp. 147-157
    • Gurney, M.E.1    Cutting, F.B.2    Zhai, P.3    Doble, A.4    Taylor, C.P.5    Andrus, P.K.6    Hall, E.D.7
  • 24
    • 0035894746 scopus 로고    scopus 로고
    • Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes
    • Gutmann DH, Wu YL, Hedrick NM, Zhu Y, Guha A, and Parada LF. Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes. Hum Mol Genet 10: 3009-3016, 2001.
    • (2001) Hum Mol Genet , vol.10 , pp. 3009-3016
    • Gutmann, D.H.1    Wu, Y.L.2    Hedrick, N.M.3    Zhu, Y.4    Guha, A.5    Parada, L.F.6
  • 25
    • 0036135131 scopus 로고    scopus 로고
    • Parkinson's genetics: An embarrassment of riches
    • Gwinn-Hardy K and Farrer M. Parkinson's genetics: an embarrassment of riches. Ann Neurol 51: 7-8, 2002.
    • (2002) Ann Neurol , vol.51 , pp. 7-8
    • Gwinn-Hardy, K.1    Farrer, M.2
  • 26
    • 0035199290 scopus 로고    scopus 로고
    • New concepts in the drug therapy of Alzheimer's disease
    • Hake AM and Farlow MR. New concepts in the drug therapy of Alzheimer's disease. Expert Opin Pharmacother 2: 1975-1983, 2001.
    • (2001) Expert Opin Pharmacother , vol.2 , pp. 1975-1983
    • Hake, A.M.1    Farlow, M.R.2
  • 27
    • 0035033889 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells
    • Han X, Sun Y, Scott S, and Bleich D. Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells. Diabetes 50: 1047-1055, 2001.
    • (2001) Diabetes , vol.50 , pp. 1047-1055
    • Han, X.1    Sun, Y.2    Scott, S.3    Bleich, D.4
  • 30
    • 0032453014 scopus 로고    scopus 로고
    • Cellular reactions to axotomy in rat superior cervical ganglia includes apoptotic cell death
    • Hou XE, Lundmark K, and Dahlstrom AB. Cellular reactions to axotomy in rat superior cervical ganglia includes apoptotic cell death. J Neurocytol 27: 441-451, 1998.
    • (1998) J Neurocytol , vol.27 , pp. 441-451
    • Hou, X.E.1    Lundmark, K.2    Dahlstrom, A.B.3
  • 32
    • 0034327342 scopus 로고    scopus 로고
    • Novel drug development for amyotrophic lateral sclerosis
    • Hurko O and Walsh FS. Novel drug development for amyotrophic lateral sclerosis. J Neurol Sci 180: 21-28, 2000.
    • (2000) J Neurol Sci , vol.180 , pp. 21-28
    • Hurko, O.1    Walsh, F.S.2
  • 33
    • 0037040491 scopus 로고    scopus 로고
    • Human α-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine
    • Junn E and Mouradian MM. Human α-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine. Neurosci Lett 320: 146-150, 2002.
    • (2002) Neurosci Lett , vol.320 , pp. 146-150
    • Junn, E.1    Mouradian, M.M.2
  • 34
    • 0033974440 scopus 로고    scopus 로고
    • Chronic mitochondrial inhibition induces selective motoneuron death in vitro: A new model for amyotrophic lateral sclerosis
    • Kaal EC, Vlug AS, Versleijen MW, Kuilman M, Joosten EA, and Bar PR. Chronic mitochondrial inhibition induces selective motoneuron death in vitro: a new model for amyotrophic lateral sclerosis. J Neurochem 74: 1158-1165, 2000.
    • (2000) J Neurochem , vol.74 , pp. 1158-1165
    • Kaal, E.C.1    Vlug, A.S.2    Versleijen, M.W.3    Kuilman, M.4    Joosten, E.A.5    Bar, P.R.6
  • 35
    • 0035895736 scopus 로고    scopus 로고
    • Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide
    • Klaidman LK, Mukherjee SK, and Adams JD Jr. Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide. Biochim Biophys Acta 1525: 136-148, 2001.
    • (2001) Biochim Biophys Acta , vol.1525 , pp. 136-148
    • Klaidman, L.K.1    Mukherjee, S.K.2    Adams J.D., Jr.3
  • 36
    • 0035918275 scopus 로고    scopus 로고
    • Selective roles of retinoic acid receptor and retinoid x receptor in the suppression of apoptosis by all-trans-retinoic acid
    • Konta T, Xu Q, Furusu A, Nakayama K, and Kitamura M. Selective roles of retinoic acid receptor and retinoid x receptor in the suppression of apoptosis by all-trans-retinoic acid. J Biol Chem 276: 12697-12701, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 12697-12701
    • Konta, T.1    Xu, Q.2    Furusu, A.3    Nakayama, K.4    Kitamura, M.5
  • 37
    • 0030910902 scopus 로고    scopus 로고
    • BAPTA-AM and ethanol protect cerebellar granule neurons from the destructive effect of the weaver gene
    • Liesi P, Wright JM, and Krauthamer V. BAPTA-AM and ethanol protect cerebellar granule neurons from the destructive effect of the weaver gene. J Neurosci Res 48: 571-579, 1997.
    • (1997) J Neurosci Res , vol.48 , pp. 571-579
    • Liesi, P.1    Wright, J.M.2    Krauthamer, V.3
  • 38
    • 0030849266 scopus 로고    scopus 로고
    • Structure and mechanism of carbonic anhydrase
    • Lindskog S. Structure and mechanism of carbonic anhydrase. Pharmacol Ther 74: 1-20, 1997.
    • (1997) Pharmacol Ther , vol.74 , pp. 1-20
    • Lindskog, S.1
  • 40
    • 0029731654 scopus 로고    scopus 로고
    • Animal models for motor neuron diseases: Research directions
    • Ludolph AC. Animal models for motor neuron diseases: research directions. Neurology 47: S228-232, 1996.
    • (1996) Neurology , vol.47
    • Ludolph, A.C.1
  • 41
    • 0035062464 scopus 로고    scopus 로고
    • Effects of amyloid peptides on cell viability and expression of neuropeptides in cultured rat dorsal root ganglion neurons: A role for free radicals and protein kinase C
    • Ma W, Zheng WH, Belanger S, Kar S, and Quirion R. Effects of amyloid peptides on cell viability and expression of neuropeptides in cultured rat dorsal root ganglion neurons: a role for free radicals and protein kinase C. Eur J Neurosci 13: 1125-1135, 2001.
    • (2001) Eur J Neurosci , vol.13 , pp. 1125-1135
    • Ma, W.1    Zheng, W.H.2    Belanger, S.3    Kar, S.4    Quirion, R.5
  • 43
    • 0034213186 scopus 로고    scopus 로고
    • The evolution of free radicals and oxidative stress
    • McCord JM. The evolution of free radicals and oxidative stress. Am J Med 108: 652-659, 2000.
    • (2000) Am J Med , vol.108 , pp. 652-659
    • McCord, J.M.1
  • 44
    • 0034643895 scopus 로고    scopus 로고
    • Oxidative stress induces intracellular accumulation of amyloid β-protein (Aβ) in human neuroblastoma cells
    • Misonou H, Morishima-Kawashima M, and Ihara Y. Oxidative stress induces intracellular accumulation of amyloid β-protein (Aβ) in human neuroblastoma cells. Biochemistry 39: 6951-6959, 2000.
    • (2000) Biochemistry , vol.39 , pp. 6951-6959
    • Misonou, H.1    Morishima-Kawashima, M.2    Ihara, Y.3
  • 46
    • 0033575294 scopus 로고    scopus 로고
    • Suppression of apoptosis by all-trans-retinoic acid. Dual intervention in the c-Jun n-terminal kinase-AP-1 pathway
    • Moreno-Manzano V, Ishikawa Y, Lucio-Cazana J, and Kitamura M. Suppression of apoptosis by all-trans-retinoic acid. Dual intervention in the c-Jun n-terminal kinase-AP-1 pathway. J Biol Chem 274: 20251-20258, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 20251-20258
    • Moreno-Manzano, V.1    Ishikawa, Y.2    Lucio-Cazana, J.3    Kitamura, M.4
  • 47
    • 0037154184 scopus 로고    scopus 로고
    • Recent advances in the genetics and pathogenesis of Parkinson disease
    • Mouradian MM. Recent advances in the genetics and pathogenesis of Parkinson disease. Neurology 58: 179-185, 2002.
    • (2002) Neurology , vol.58 , pp. 179-185
    • Mouradian, M.M.1
  • 48
    • 0031296826 scopus 로고    scopus 로고
    • Psychophysiological aspects of motion sickness
    • Murray JB. Psychophysiological aspects of motion sickness. Percept Mot Skills 85: 1163-1167, 1997.
    • (1997) Percept Mot Skills , vol.85 , pp. 1163-1167
    • Murray, J.B.1
  • 50
    • 0032430185 scopus 로고    scopus 로고
    • Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase
    • Pasinelli P, Borchelt DR, Houseweart MK, Cleveland DW, and Brown RH Jr. Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proc Natl Acad Sci USA 95: 15763-15768, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15763-15768
    • Pasinelli, P.1    Borchelt, D.R.2    Houseweart, M.K.3    Cleveland, D.W.4    Brown R.H., Jr.5
  • 51
    • 0020320148 scopus 로고
    • Antioxidation theory of non-steroidal anti-inflammatory drugs based upon the inhibition of luminol-enhanced chemiluminescence from the myeloperoxidase reaction
    • Pekoe G, Van Dyke K, Peden D, Mengoli H, and English D. Antioxidation theory of non-steroidal anti-inflammatory drugs based upon the inhibition of luminol-enhanced chemiluminescence from the myeloperoxidase reaction. Agents Actions 12: 371-376, 1982.
    • (1982) Agents Actions , vol.12 , pp. 371-376
    • Pekoe, G.1    Van Dyke, K.2    Peden, D.3    Mengoli, H.4    English, D.5
  • 52
    • 0034992374 scopus 로고    scopus 로고
    • Extracting knowledge from dynamics in gene expression
    • Reis BY, Butte AS, and Kohane IS. Extracting knowledge from dynamics in gene expression. J Biomed Inform 34: 15-27, 2001.
    • (2001) J Biomed Inform , vol.34 , pp. 15-27
    • Reis, B.Y.1    Butte, A.S.2    Kohane, I.S.3
  • 55
    • 0035226263 scopus 로고    scopus 로고
    • The pathogenesis of ALS: Implications for treatment strategies
    • Silani V, Braga M, Cardin V, and Scarlato G. The pathogenesis of ALS: implications for treatment strategies. Neurol Neurochir Pol 35: 25-39, 2001.
    • (2001) Neurol Neurochir Pol , vol.35 , pp. 25-39
    • Silani, V.1    Braga, M.2    Cardin, V.3    Scarlato, G.4
  • 56
    • 0035516099 scopus 로고    scopus 로고
    • RET oncogene activation in papillary thyroid carcinoma
    • Tallini G and Asa SL. RET oncogene activation in papillary thyroid carcinoma. Adv Anat Pathol 8: 345-354, 2001.
    • (2001) Adv Anat Pathol , vol.8 , pp. 345-354
    • Tallini, G.1    Asa, S.L.2
  • 62
    • 0033825627 scopus 로고    scopus 로고
    • Oxidative stress and genetics in the pathogenesis of Parkinson's disease
    • Zhang Y, Dawson VL, and Dawson TM. Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol Dis 7: 240-250, 2000.
    • (2000) Neurobiol Dis , vol.7 , pp. 240-250
    • Zhang, Y.1    Dawson, V.L.2    Dawson, T.M.3


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