Restricted polymorphisms of the mannose-binding lectin gene in a population of Papua New Guinea

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 505, Issue 1-2, 2002, Pages 87-91

  Jüliger, Simone ^a   Kremsner, Peter G ^a   Alpers, Michael P ^b   Reeder, John C ^b   Kun, Jürgen F J ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

Author keywords

Mannose binding lectin; Papua New Guinea; Polymorphism; Promoter

Indexed keywords

ASPARTIC ACID; GLYCINE; LECTIN; MANNOSE BINDING PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXON; GENE FUNCTION; HUMAN; MALARIA; PAPUA NEW GUINEA; PARASITOSIS; PLASMODIUM FALCIPARUM; POLYMORPHIC LOCUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL;

5' UNTRANSLATED REGIONS; BASE SEQUENCE; CARRIER PROTEINS; CHROMOSOMES, HUMAN, PAIR 10; COLLECTINS; DNA MUTATIONAL ANALYSIS; EXONS; GENE FREQUENCY; HUMANS; MALARIA, FALCIPARUM; MOLECULAR SEQUENCE DATA; PAPUA NEW GUINEA; POINT MUTATION; PROMOTER REGIONS (GENETICS); SEQUENCE DELETION; VARIATION (GENETICS);

PLASMODIUM FALCIPARUM;

EID: 0037194650     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(02)00142-2     Document Type: Article

References (23)

1. Binding of mannan-binding protein to various bacterial pathogens of meningitis
2. Mannose-binding lectin binds to a range of clinically relevant microorganisms and promotes complement deposition
3. Secreted proteophosphoglycan of Leishmania mexicana amastigotes activates complement by triggering the mannan binding lectin pathway
4. Recognition of the major cell surface glycoconjugates of Leishmania parasites by the human serum mannan-binding protein
5. The major surface glycoprotein of Trypanosoma cruzi amastigotes are ligands of the human serum mannose-binding protein
6. Schistosoma mansoni: Adhesion of mannan-binding lectin to surface glycoproteins of cercariae and adult worms
7. Recognition of Plasmodium falciparum proteins by mannan-binding lectin, a component of the human innate immune system
8. Mannose-binding lectin: The pluripotent molecule of the innate immune system
9. The role of mannose-binding proteins in host defense
10. The human mannose-binding protein gene. Exon structure reveals its evolutionary relationship to a human pulmonary surfactant gene and localization to chromosome 10
11. Mannose-binding lectin plasma levels and gene polymorphisms in Plasmodium falciparum malaria
12. Dual role of mannan-binding protein in infections: Another case of heterosis?
13. Mannan-binding lectin enhances susceptibility to visceral leishmaniasis
14. High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene
15. Mutations in the human mannose-binding protein gene: Frequencies in several population groups
16. Promoter variants of the human mannose-binding lectin gene show different binding abilities
17. Structure and evolutionary origin of the gene encoding a human serum mannose-binding protein
18. Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America
19. Characterization of human serum mannan-binding protein promoter
20. Restricted polymorphism of the mannose-binding lectin gene of indigenous Australians
21. Whole genome amplification from a single cell: Implications for genetic analysis
22. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein
23. Mannose binding lectin (MBL) genotype distributions with relation to serum levels in UK Caucasoids