A mutation in the human neurofilament M gene in Parkinson's disease that suggests a role for the cytoskeleton in neuronal degeneration

Neuroscience Letters

Volumn 322, Issue 1, 2002, Pages 57-61

  Lavedan, Christian ^a   Buchholtz, Stephanie ^a   Nussbaum, Robert L ^b   Albin, Roger L ^c,d   Polymeropoulos, Mihael H ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

Cytoskeleton; Gly336Ser; Lewy bodies; Mutation; Neurofilament M; Parkinson's disease

Indexed keywords

NEUROFILAMENT PROTEIN; PROTEIN SUBUNIT;

ADULT; AMINO ACID SEQUENCE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DISEASE SEVERITY; DOPAMINERGIC NERVE CELL; HUMAN; MUTATION; NERVE CELL DEGENERATION; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SUBSTANTIA NIGRA;

ADULT; AGE OF ONSET; BRAIN; CYTOSKELETON; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC SCREENING; GLYCINE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; NEUROFILAMENT PROTEINS; NEURONS; PARKINSONIAN DISORDERS; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SERINE;

EID: 0037192440     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)02513-7     Document Type: Article

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