Sequence conservation between mouse and human synphilin-1

Neuroscience Letters

Volumn 322, Issue 1, 2002, Pages 9-12

  O'Farrell, Casey ^a   Pickford, Fiona ^a   Vink, Liselot ^a   McGowan, Eileen ^a   Cookson, Mark R ^a  

^a MAYO CLINIC   (United States)

Author keywords

synuclein; Mouse homologue; Parkinson's disease

Indexed keywords

ANKYRIN; BRAIN PROTEIN; PROTEIN DERIVATIVE; SYNPHILIN 1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BRAIN; CONTROLLED STUDY; HUMAN; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE;

ALPHA-SYNUCLEIN; ANIMALS; ANKYRIN REPEAT; BINDING SITES; BRAIN; CARRIER PROTEINS; CLONING, MOLECULAR; GENE EXPRESSION REGULATION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; PARKINSON DISEASE; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SYNUCLEINS;

EID: 0037192418     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00068-X     Document Type: Article

References (6)

1. Ankyrins and cellular targeting of diverse membrane proteins to physiological sites
2. Coiled coils: A highly versatile protein folding motif
3. Parkin ubiquitinates the α-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
4. Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions
5. Transfected synphilin-1 forms cytoplasmic inclusions in HEK293 cells
6. Mutation in the α-synuclein gene identified in families with Parkinson's disease