Nobel prize for physiology or medicine 2002 is awarded for research into the genetic regulation of organ development and programmed cell death;Nobelprijs fysiologie of geneeskunde 2002 voor onderzoek naar de genetische regulatie van orgaanontwikkeling en geprogrammeerde celdood

Nederlands Tijdschrift voor Geneeskunde

Volumn 146, Issue 52, 2002, Pages 2525-2527

  Dijkstra, C D ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACHIEVEMENT; ADULT; APOPTOSIS; CAENORHABDITIS ELEGANS; CELL COUNT; CELL DIFFERENTIATION; CELL DIVISION; CELL MATURATION; CELL REGENERATION; CELL SPECIFICITY; CELL TYPE; EMBRYO; EMBRYO DEVELOPMENT; EXPERIMENTAL MODEL; FERTILIZATION; FETUS; FETUS DEVELOPMENT; GENE FUNCTION; GENETIC REGULATION; HUMAN; MEDICAL RESEARCH; ORGANOGENESIS; PATHOGENESIS; PHYSIOLOGY; SHORT SURVEY;

ANIMALS; APOPTOSIS; DEVELOPMENTAL BIOLOGY; ENGLAND; GENETICS; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HUMANS; MODELS, GENETIC; NOBEL PRIZE; ORGANOGENESIS; UNITED STATES;

EID: 0037192065     PISSN: 00282162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (12)

1. Benedictus R. Eén worm, 959 cellen en drie onderzoekers. NRC Handelsblad 29 oktober 2002 p. 9.
2. Brown A. One man and his worm. The Guardian Europe 9 oktober 2002 p. 1-3.
3. Ward S, Thomson N, White JG, Brenner S. Elektron microscopical reconstruction of the anterior sensory anatomy of the nematode Caenorhabditis elegans. J Comp Neurol 1975;160:313-37.
4. Sulston J, Dew M, Brenner S. Dopaminergic neurons in the nematode Caenorhabditis elegans. J Comp Neurol 1975;163:215-26.
5. Sulston JE. Post-embryonic development in the ventral cord of Caenorhabditis elegans. Philos Trans R Soc Lond B Biol Sci 1976; 275:287-97.
6. Sulston JE, Horvitz HR. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev Biol (N Y 1985) 1977;56:100-56.
7. Chalfie M, Horvitz HR, Sulston JE. Mutations that lead to reiterations in the cell lineages of C. elegans. Cell 1981;24:59-69.
8. Ward S, Burke DJ, Sulston JE, Coulson AR, et al. Genomic organization of major sperm protein genes and pseudogenes in the nematode Caenorhabditis elegans. J Mol Biol 1988;199:1-139
9. Yuan J, Horvitz HR. The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death. Development 1992;116 Suppl: 309-20.
10. Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 1993;75:641-52.
11. Hengartner MO, Ellis RE, Horvitz HR. Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature 1992;356:494-9.
12. Hengartner MO, Horvitz HR. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 1994;76:665-76.