Withdrawal from chronic ethanol increases the sensitivity of presynaptic 5-HT1A receptors modulating serotonin and dopamine synthesis in rat brain in vivo

Neuroscience Letters

Volumn 326, Issue 2, 2002, Pages 121-124

  Esteban, Susana ^a   Moranta, David ^a   Sastre Coll, Antoni ^a   Miralles, Antonio ^a   García Sevilla, Jesús A ^a,b  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

3,4 Dihydroxyphenylalanine dopamine synthesis; 5 Hydroxytryptophan serotonin synthesis; 8 Hydroxy 2 di n propylamino tetralin; Ethanol dependence and withdrawal; Rat brain; Serotonin1A auto and heteroreceptors

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ALCOHOL; BUSPIRONE; DOPAMINE; PRESYNAPTIC RECEPTOR; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR;

ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE METABOLISM; DOSE RESPONSE; DRUG EFFECT; LONG TERM EXPOSURE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR SENSITIVITY; SEROTONIN METABOLISM;

5-HYDROXYTRYPTOPHAN; 8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BRAIN; BUSPIRONE; CEREBRAL CORTEX; CHRONIC DISEASE; CORPUS STRIATUM; DIHYDROXYPHENYLALANINE; DOPAMINE; ETHANOL; HIPPOCAMPUS; MALE; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN; SEROTONIN AGONISTS; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0037189080     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00313-0     Document Type: Article

References (17)

1. 3 receptors in Fawn-Hooded rats: A quantitative autoradiography study
2. Regional brain contents of serotonin, dopamine and their metabolites in the selectively bred high- and low-alcohol drinking lines of rats
3. 1A receptors in ethanol dependence
4. Regional serotonin-1A receptors in the CNS of alcohol-preferring and -nonpreferring rats
5. Association between low contents of dopamine and serotonin in the nucleus accumbens and high alcohol preference
6. Ritanserin decreases alcohol intake in chronic alcoholics
7. Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats
8. The serotonin inhibitor citalopram attenuates ethanol intake
9. 1B receptor subtypes in rat brain
10. SDZ-205,152, a novel dopamine receptor agonist, reduces oral ethanol self-administration in rats
11. Effects of imidazoline receptor ligands on monoamine synthesis in the rat brain in vivo
12. 5-HT and alcohol abuse
13. Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats
14. Higher density of serotonin-1A receptors in the hippocampus and cerebral cortex of alcohol-preferring P rats
15. Greater abundance of serotonin-1A receptor in some brain areas of alcohol-preferring (P) rats compared to nonpreferring (NP) rats
16. Reexamination of the relationship between alcohol preference and brain monoamines in inbred strains of mice including senescence-accelerated mice
17. Alcohol stimulates the release of dopamine and serotonin in the nucleus accumbens