The serine proteinase thrombin promotes migration of human renal carcinoma cells by a PKA-dependent mechanism

Cancer Letters

Volumn 180, Issue 2, 2002, Pages 183-190

  Kaufmann, R ^a   Junker, U ^b   Junker, K ^a   Nuske, K ^a   Ranke, C ^a   Zieger, M ^a   Scheele, J ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b BAYER PHARMA AG   (Germany)

Author keywords

cAMP dependent protein kinase A; Migration; Renal carcinoma; Signaling; Thrombin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BISINDOLYLMALEIMIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN KINASE INHIBITOR; SERINE PROTEINASE; THROMBIN;

ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; PRIORITY JOURNAL;

CELL DIVISION; CELL MOVEMENT; CELL NUCLEUS; CHEMOTAXIS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; HUMANS; KIDNEY NEOPLASMS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PROTEIN KINASE C; THROMBIN; TRANSCRIPTION FACTOR RELA; TUMOR CELLS, CULTURED;

EID: 0037189035     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00870-9     Document Type: Article

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