Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid

Toxicology

Volumn 181-182, Issue , 2002, Pages 223-227

  Winterbourn, Christine C ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Chlorotyrosine; Glutathione; Hypochlorous acid; Myeloperoxidase; Neutrophil

Indexed keywords

ANTIBODY; BIOLOGICAL MARKER; CARBONYL DERIVATIVE; CHLORIDE; CHLOROHYDRIN DERIVATIVE; FREE RADICAL; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; MYELOPEROXIDASE; OXIDIZING AGENT; PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

CATALYSIS; CELL STIMULATION; CHLORINATION; DISEASE SEVERITY; HUMAN; INFLAMMATION; INJURY; NEUTROPHIL; OXIDATION; PATHOGENESIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; REVIEW; TOXICITY;

EID: 0037184780     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00286-X     Document Type: Article

References (25)

1. Buss I.H., Chan T.P., Sluis K.B., Domigan N.M., Winterbourn C.C. Protein carbonyl measurement by a sensitive ELISA method. Free Radical Biol. Med. 23:1997;361-366.
2. Carr A.C., Domigan N.M., Vissers M.C.M., Winterbourn C.C. Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins. Redox Rep. 3:1997a;263-271.
3. Carr A.C., Winterbourn C.C. Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid. Biochem. J. 327:1997b;275-281.
4. Chapman A.L.P., Senthilmohan R., Winterbourn C.C., Kettle A.J. Comparison of mono and dichlorinated tyrosines with carbonyls for detection of hypochlorous acid-modified proteins. Arch. Biochem. Biophys. 377:2000;95-100.
5. Domigan N.M., Charlton T.S., Duncan M.W., Winterbourn C.C., Kettle A.J. Chlorination of tyrosyl residues in peptides by myeloperoxidase and human neutrophils. J. Biol. Chem. 270:1995;16542-16548.
6. Hazell L.J., Arnold L., Flowers D., Waeg G., Malle E., Stocker R. Presence of hypochlorite-modified proteins in human atherosclerotic lesions. J. Clin. Invest. 97:1996;1535-1544.
7. Hazell L.J., van den Berg J.J., Stocker R. Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation. Biochem. J. 302:1994;297-304.
8. Hazen S.L., Heinecke J.W. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J. Clin. Invest. 99:1997;2075-2081.
9. Heinecke J.W., Hsu F.F., Crowley J.R., Hazen S.L., Leeuwenburgh C., Mueller D.M., Rasmussen J.E., Turk J. Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues. Methods Enzymol. 300:1999;124-144.
10. Heinecke J.W., Li W., Mueller D.M., Bohrer A., Turk J. Cholesterol chlorohydrin synthesis by the myeloperoxidase-hydrogen peroxide-chloride system: potential markers for lipoproteins oxidatively damaged by phagocytes. Biochemistry. 33:1994;10127-10136.
11. Jerlich A., Pitt A.R., Schaur R.J., Spickett C.M. Pathways of phospholipid oxidation by HOCl in human LDL detected by LC-MS. Free Radical Biol. Med. 28:2000;673-682.
12. Kettle A.J. Neutrophils convert tyrosyl residues in albumin to chlorotyrosine. FEBS Lett. 379:1996;103-106.
13. Klebanoff S.J. Oxygen metabolites from phagocytes. Gallin J.I., Snyderman R. Inflammation: Basic Principles and Clinical Correlates. 1999;721-768 Lippincott Williams & Wilkins, Philadelphia.
14. Malle E., Woenckhaus C., Waeg G., Esterbauer H., Grone E.F., Grone H.-J. Immunological evidence for hypochlorite-modified proteins in human kidney. Am. J. Pathol. 150:1997;603-615.
15. Midwinter, R.G., Vissers, M.C.M., Winterbourn, C.C., 2001. Hypochlorous acid stimulation of the MAP-kinase pathway enhances cell survival. Arch. Biochem. Biophys. 394, 13-20.
16. Peskin A.V., Winterbourn C.C. Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate. Free Radical Biol. Med. 30:2001;572-579.
17. Prutz W.A., Kissner R., Koppenol W.H., Ruegger H. On the irreversible destruction of reduced nicotinamide nucleotides by hypohalous acids. Arch. Biochem. Biophys. 380:2000;181-191.
18. Pullar, J.M., Vissers, M.C. Winterbourn, C.C. Glutathione oxidation by hypochlorous acid in endothelial cells produces glutathione sulfonamide as a major product but not glutathione disulfide. J. Biol. Chem., in Press.
19. Pullar J.M., Winterbourn C.C., Vissers M.C.M. Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid. Am. J. Physiol. 277:1999;H1505-1512.
20. van der Vliet A., Nguyen M.N., Shigenaga M.K., Eiserich J.P., Marelich G.P., Cross C.E. Myeloperoxidase and protein oxidation in cystic fibrosis. Am. J. Physiol. 279:2000;L537-L546.
21. Vile G.F., Rothwell L.A., Kettle A.J. Initiation of rapid, p53-dependent growth arrest in cultured human skin fibroblasts by reactive chlorine species. Arch. Biochem. Biophys. 377:2000;122-128.
22. Vissers M.C.M., Pullar J.M., Hampton M.B. Low-level exposure to hypochlorous acid causes apoptosis or growth arrest in human endothelial cells. Biochem. J. 344:1999;443-449.
23. Winterbourn C.C. Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite. Biochim. Biophys. Acta. 840:1985;204-210.
24. Winterbourn C.C., Brennan S.O. Characterisation of the oxidation products of the reaction between reduced glutathione and hypochlorous acid. Biochem. J. 326:1997;87-92.
25. Winterbourn C.C., van den Berg J.J.M., Roitman E., Kuypers F.A. Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid. Arch. Biochem. Biophys. 296:1992;547-555.