The effect of alcohol on acetaminophen hepatotoxicity [1]

Archives of Internal Medicine

Volumn 162, Issue 10, 2002, Pages 1193-

  Holtzman, Jordan L ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 2E1; DRUG METABOLITE; N ACETYL 4 BENZOQUINONEIMINE; PARACETAMOL; UNCLASSIFIED DRUG;

ALCOHOL ABUSE; ALCOHOL LIVER DISEASE; DRUG ALCOHOL INTERACTION; DRUG PROTEIN BINDING; HUMAN; LETTER; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0037182014     PISSN: 00039926     EISSN: None     Source Type: Journal    
DOI: 10.1001/archinte.162.10.1193     Document Type: Letter

References (5)

1. Effect of maximum daily doses of acetaminophen on the liver of alcoholic patients: A randomized, double-blind, placebo-controlled trial
2. Potentiation of acetaminophen hepatotoxicity by alcohol
3. The covalent binding of [14C]-acetaminophen to mouse hepatic microsomal proteins: The specific binding to calreticulin and the two forms of the thiol: Protein disulfide oxidoreductases
4. Ethanol induction of acetaminophen toxicity and metabolism
5. Catalysis of the cysteine conjugation and protein binding of acetaminophen by microsomes from a human lymphoblast line transfected with the cDNAs of various forms of human cytochrome P450