Primed CTLs specific for HLA class I may still be present in sensitized patients when anti-HLA antibodies have disappeared: Relevance for donor selection

Transplantation

Volumn 73, Issue 8, 2002, Pages 1286-1290

  Van Kampen, Corine A ^a   Versteeg Van Der Voort Maarschalk, Minke F J ^a   Roelen, Dave L ^a   Claas, Frans H J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIBODY; HLA ANTIGEN CLASS 1;

ARTICLE; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; HLA MATCHING; HUMAN; IMMUNE SYSTEM; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; ORGAN DONOR; PRIORITY JOURNAL; SENSITIZATION;

EID: 0037181645     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200204270-00017     Document Type: Article

References (21)

1. Transplantation of highly sensitized patients on the basis of acceptable HLA-A and B mismatches
2. Cells mediating allograft rejection
3. Immunoglobulin class and specificity of antibodies causing positive T cell crossmatches
4. Characterization of lymphocytotoxic antibodies causing a positive crossmatch in renal transplantation
5. Evidence that antibody formation against a certain HLA alloantigen is associated not with a quantitative but with a qualitative change in the cytotoxic T cells recognizing that particular same antigen
6. IgG antibodies against an HLA antigen are associated with activated cytotoxic T cells against this antigen, IgM are not
7. Differential role of naive versus primed cytotoxic T cells in clinical transplantation
8. Differential avidity and cyclosporine sensitivity of committed donor-specific graft-infiltrating cytotoxic T cells and their precursors
9. The presence of activated donor HLA class I-reactive T lymphocytes is associated with rejection of corneal grafts
10. Clonal heterogeneity in the functional requirement for lyt-2/3 molecules on cytolytic T lymphocytes (CTL): Possible implications for the affinity of CTL antigen receptors
11. Evaluation of dithiothreitol (DTT) for inactivation of IgM antibodies
12. Determination of cytotoxic T-lymphocyte precursor frequencies using europium labeling as a non-radioactive alternative to labeling with chromium-51
13. Limiting dilution assays; experimental design and statistical analysis
14. Analysis of cytotoxic T cell precursor frequencies directed against individual HLA-A and -B alloantigens
15. The influence of workshop monoclonal antibodies on CML, PLT, ADCC and NK activity: Functional studies with workshop antibodies
16. Pregnancy can induce longpersisting primed CTLs specific for inherited paternal HLA antigens
17. Graft outcome in the multiple transplant patient with a positive donor cross-match with non-current sera
18. Successful cadaver kidney transplantation in patients highly sensitized by blood transfusions
19. Specificity and Ig Class of preformed alloantibodies causing a positive crossmatch in renal transplantation
20. Anti-idiotypic antibodies specific for HLA in heart and kidney allograft recipients
21. The avidity, not the mere presence, of primed cytotoxic T-lymphocytes for donor human leukocyte class II antigens determines their clinical relevance after heart transplantation