Chemical models for cytochrome P450 as a biomimetic metabolic activation system in mutation assays

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 519, Issue 1-2, 2002, Pages 133-140

  Inami, Keiko ^a   Mochizuki, Masataka ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Chemical model; Cytochrome P450; Metabolic activation; Oxidant; Porphyrin

Indexed keywords

2 FLUORENYLAMINE; 3 CHLOROPERBENZOIC ACID; ACETONITRILE; AROMATIC AMINE; BENZO[A]PYRENE; CARCINOGEN; CYTOCHROME P450; DIOXANE; INDOLE DERIVATIVE; IRON COMPLEX; N (2 FLUORENYL)ACETAMIDE; N,N DIMETHYLFORMAMIDE; OXIDIZING AGENT; PHTHALIC ACID DERIVATIVE; POLYCYCLIC HYDROCARBON;

ARTICLE; ASSAY; BIOMIMETICS; CHEMICAL MODEL; CONTROLLED STUDY; FRAMESHIFT MUTATION; METABOLIC ACTIVATION; MICROSOME; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM;

2-ACETYLAMINOFLUORENE; BENZO(A)PYRENE; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME ACTIVATION; FERRIC COMPOUNDS; METALLOPORPHYRINS; MODELS, CHEMICAL; MUTAGENICITY TESTS; MUTAGENS; MUTATION; NITROSAMINES; OXIDANTS; PEROXIDES; SALMONELLA TYPHIMURIUM; SOLVENTS;

SALMONELLA TYPHIMURIUM;

EID: 0037179202     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(02)00132-8     Document Type: Article

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