Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT3

Journal of Medicinal Chemistry

Volumn 45, Issue 9, 2002, Pages 1853-1859

  Leclerc, Véronique ^a   Yous, Saïd ^a   Delagrange, Philippe ^b   Boutin, Jean A ^c   Renard, Pierre ^b   Lesieur, Daniel ^a  

^a Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^c INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROCYCLIC AMINE; INDOLE DERIVATIVE; MELATONIN; MELATONIN RECEPTOR; NITROINDOLE DERIVATIVE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL STRUCTURE; CONTROLLED STUDY; HAMSTER; HUMAN; HUMAN CELL; ISOMERISM; LIGAND BINDING; NITRATION; NONHUMAN; PINEAL BODY; RECEPTOR BINDING;

ACETAMIDES; ANIMALS; BINDING SITES; CELL LINE; CRICETINAE; HUMANS; INDOLES; LIGANDS; NITRO COMPOUNDS; RADIOLIGAND ASSAY; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037171722     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm011053+     Document Type: Article

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