Fulminant hepatitis and fatal toxic epidermal necrolysis (Lyell disease) coincident with clarithromycin administration in an alcoholic patient receiving disulfiram therapy

Archives of Internal Medicine

Volumn 162, Issue 4, 2002, Pages 474-476

  Masiá, Mar ^a   Gutiérrez, Félix ^a   Jimeno, Araceli ^a   Navarro, Andrés ^a   Borrás, Joaquín ^a   Matarredona, Jaime ^a   Martín Hidalgo, Alberto ^a  

^a HOSPITAL GENERAL UNIVERSITARIO DE ELCHE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CLARITHROMYCIN; CYTOCHROME P450; DISULFIRAM;

ADULT; ALCOHOLISM; ARTICLE; BILIRUBIN BLOOD LEVEL; CASE REPORT; CLINICAL FEATURE; DISEASE COURSE; DRUG METABOLISM; HEPATITIS; HUMAN; LIVER FUNCTION; LIVER TRANSPLANTATION; MALE; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; RESPIRATORY TRACT INFECTION; TOXIC EPIDERMAL NECROLYSIS;

EID: 0037169961     PISSN: 00039926     EISSN: None     Source Type: Journal    
DOI: 10.1001/archinte.162.4.474     Document Type: Article

References (11)

1. Disulfiram treatment of alcoholism
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4. An in vitro model for predicting in vivo inhibition of CYP4503A4 by metabolic intermediate complex formation
5. Prevention of acetaminophen hepatotoxicity by disulfiram
6. Disulfiram induced hepatitis: Report of four cases and review of the literature
7. Overview of the tolerability profile of clarithromycin in preclincal and clinical trials
8. Anti-infective agents: Macrolides
9. Hepatitis, toxic epidermal necrolysis and pancreatitis in association with sulindac therapy
10. Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis: Report of a patient treated with corticosteroid "pulse therapy."
11. Ischemic hepatitis associated with toxic epidermal necrolysis in a cirrhotic patient treated with cefuroxime