Intralesion transplantation of serotonergic precursors enhances locomotor recovery but has no effect on development of chronic central pain following hemisection injury in rats

Neuroscience Letters

Volumn 324, Issue 3, 2002, Pages 222-226

  Hains, Bryan C ^a,b   Yucra, Jennifer A ^a   Eaton, Mary J ^c   Hulsebosch, Claire E ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MIAMI   (United States)

Author keywords

Brain derived neurotrophic factor; Locomotion; Pain; Serotonin; Spinal cord injury; Transplantation

Indexed keywords

NEUROTROPHIC FACTOR; SEROTONIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BRAIN REGION; CELL TRANSPLANTATION; CELL TYPE; CHRONIC DISEASE; CONTROLLED STUDY; CONVALESCENCE; DISEASE COURSE; HYPERALGESIA; IMMUNE DEFICIENCY; INTERMETHOD COMPARISON; LOCOMOTION; MALE; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SOMATOSENSORY SYSTEM; SPINAL CORD HEMISECTION; SPINAL CORD INJURY; TIME; TREATMENT OUTCOME;

ANIMALS; BRAIN TISSUE TRANSPLANTATION; CELLS, CULTURED; CHRONIC DISEASE; GAIT DISORDERS, NEUROLOGIC; INJECTIONS, SPINAL; MALE; NEURONS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECOVERY OF FUNCTION; SEROTONIN; SPINAL CORD; SPINAL CORD INJURIES; STEM CELL TRANSPLANTATION; STEM CELLS; SUBARACHNOID SPACE; TREATMENT OUTCOME;

EID: 0037166072     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00194-5     Document Type: Article

References (20)

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7. Transplants of adrenal medullary chromaffin cells reduce forelimb and hindlimb allodynia in a rodent model of chronic central pain after spinal cord hemisection injury
8. Engraftment of immortalized serotonergic neurons enhances locomotor function and attenuates chronic central pain following spinal hemisection injury in the rat
9. Subdural engraftment of serotonergic neurons following spinal hemisection restores spinal serotonin, downregulates serotonin transporter, and increases BDNF tissue content in rat
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11. Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury
12. Initiation of locomotion from the mammalian brainstem
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