Activation of IP and EP3 receptors alters cAMP-dependent cell migration

European Journal of Pharmacology

Volumn 444, Issue 1-2, 2002, Pages 31-37

  Blindt, Rüdiger ^a   Bosserhoff, Anja K ^b   vom Dahl, Jürgen ^a   Hanrath, Peter ^a   Schrör, Karsten ^c   Hohlfeld, Thomas ^c   Meyer Kirchrath, Jutta ^c  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

cAMP; Cell migration; EP3 receptor; IP receptor

Indexed keywords

CYCLIC ADENOSINE 5' TRIMETAPHOSPHATE; CYCLIC ADENOSINE-5'-TRIMETAPHOSPHATE; CYCLIC AMP; DRUG DERIVATIVE; ILOPROST; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN EP3 RECEPTOR; PROSTAGLANDIN RECEPTOR; PTGIR PROTEIN, HUMAN; 11 DEOXY 16 PHENOXY 17,18,19,20 TETRANORPROSTAGLANDIN E1; FORSKOLIN; PROSTACYCLIN RECEPTOR;

ANIMAL; ARTICLE; CELL CULTURE; CELL MOTION; CHO CELL; DRUG EFFECT; HAMSTER; HUMAN; METABOLISM; VASCULAR SMOOTH MUSCLE; ANIMAL CELL; CELL MIGRATION; CHEMOTAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CHO CELLS; CRICETINAE; CYCLIC AMP; HUMANS; ILOPROST; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, PROSTAGLANDIN; RECEPTORS, PROSTAGLANDIN E; ANIMAL; HAMSTERS; HUMAN;

EID: 0037165820     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01607-2     Document Type: Article

References (27)

1. Quantitative studies on the effect of prostacyclin on freshly isolated rat osteoclasts in culture
2. Rho-Rho kinase is involved in smooth muscle cell migration through myosin light chain phosphorylation-dependent and independent pathways
3. Inhibition of neointima formation after experimental coronary artery stenting
4. Polybrene/DMSO-assisted gene transfer. Generating stable transfectants with nanogram amounts of DNA
5. Cyclooxygenase-1 and -2 dependent prostacyclin formation in patients with atherosclerosis
6. Abciximab inhibits the migration and invasion potential of human coronary artery smooth muscle cells
7. Effect of platelet-activating factor receptor expression on CHO cell motility
8. Failure of epoprostenol (prostacyclin, PGI2) to inhibit platelet aggregation and to prevent restenosis after coronary angioplasty: Results of a randomised placebo controlled trial
9. Two isoforms of prostaglandin EP3 receptor exhibiting constitutive activity and agonist-dependent activity in rho-mediated stress fiber formation
10. Desensitization of platelets to iloprost. Loss of specific binding sites and heterologous desensitization of adenylate cyclase
11. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells
12. Effect of short-term prostacyclin administration on restenosis after percutaneous transluminal coronary angioplasty
13. Arterial response to mild balloon injury in the normal rabbit: Evidence for low proliferation rate in the adventitia
14. Inhibition of ACAT activity after 7-oxo-PGI2 treatment in cholesterol-fed rabbits
15. Analysis of a porcine EP3-receptor: Cloning, expression and signal transduction
16. Chemotaxis of chinese hamster ovary cells expressing the human neutrophil formyl peptide receptor: Role of signal transduction molecules and alpha 5beta1 integrin
17. An overview of the vascular response to injury: A tribute to the late Russell Ross
18. Agonist-induced long-term desensitization of the human prostacyclin receptor
19. Rho GTPases control polarity, protrusion, and adhesion during cell movement
20. RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism
21. Synergistic inhibition of vascular smooth muscle cell migration by phosphodiesterase 3 and phosphodiesterase 4 inhibitors
22. Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions
23. Role of rho-associated kinase in neointima formation after vascular injury
24. Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats
25. Regulation of expression of matrix metalloproteinase-9 in early human T cells of the HSB.2 cultured line by the EP3 subtype of prostaglandin E2 receptor
26. Tolerance development to antimitogenic actions of prostacyclin but not of prostaglandin E1 in coronary artery smooth muscle cells