The room temperature preparation of the 1-chloro-2,2-difluorovinylzinc reagent from HCFC-133a (CF3CH2Cl). The first ambient, high yield, one-flask preparation of α-chloro-β,β-difluorostyrenes

Tetrahedron Letters

Volumn 43, Issue 39, 2002, Pages 6979-6982

  Anilkumar, R ^a   Burton, Donald J ^a  

^a E11 SSH   (United States)

Author keywords

chloro , difluorostyrene; Chlorodifluorovinyllithium; Chlorodifluorovinylzinc; HCFC 133a; Pd(0) coupling

Indexed keywords

1 CHLORO 2,2 DIFLUOROVINYLZINC; STYRENE DERIVATIVE; UNCLASSIFIED DRUG; ZINC CHLORIDE; ZINC DERIVATIVE;

ARTICLE; CATALYSIS; COMPLEX FORMATION; HYDROLYSIS; ROOM TEMPERATURE; SYNTHESIS;

EID: 0037163257     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01591-5     Document Type: Article

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15. 19F NMR: -76.6 (d, J=54.5 Hz) and -90.9 (d, J=55.0 Hz).
16. 19F NMR spectrum of the bis-reagent 5 exhibits a doublet at -76.4 ppm (J=58.3 Hz) and a doublet at -92.2 ppm (J=59.0 Hz).
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