Distinctly abnormal brain metabolism in late-onset ornithine transcarbamylase deficiency

Neurology

Volumn 59, Issue 2, 2002, Pages 210-214

  Takanashi, J ^a,b   Kurihara, A ^a   Tomita, M ^a,b   Kanazawa, M ^a   Yamamoto, S ^a   Morita, F ^a   Ikehira, H ^b   Tanada, S ^b   Kohno, Y ^a  

^a CHIBA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; GLUTAMIC ACID; GLUTAMINE;

ADOLESCENT; ADULT; AGED; ANALYTIC METHOD; ARTICLE; BIOACCUMULATION; BRAIN METABOLISM; CALCULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DISORDERS OF AMINO ACID AND PROTEIN METABOLISM; FEMALE; HEPATIC ENCEPHALOPATHY; HUMAN; JAPAN; LATENT PERIOD; MALE; NEUROCHEMISTRY; ONSET AGE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN DEPLETION; SPECTROSCOPY; TECHNIQUE;

EID: 0037162369     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.59.2.210     Document Type: Article

References (24)

1. Urea cycle enzymes
2. Hepatic encephalopathy
3. The clinical significance of metabolites
4. Subclinical hepatic encephalopathy: Proton MR spectroscopic abnormalities
5. Proton magnetic resonance spectroscopy studies on human brain myoinositol in hypo-osmolarity and hepatic encephalopathy
6. Proton MR spectroscopic measurement of neurometabolites in hepatic encephalopathy during oral lactulose therapy
7. Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis
8. Proton magnetic resonance spectroscopy: The new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy
9. 1H spectroscopy of the brain metabolites in hepatic encephalopathy: Time-course of renormalization after liver transplantation
10. 1H MR spectroscopy and neuropsychologic status of patients with hepatic encephalopathy
11. Localized proton MR spectroscopy in infants with urea cycle defect
12. Magnetic resonance spectroscopy shows increased brain glutamine in ornithine carbamoyl transferase deficiency
13. Clinical tools for the 90s: Magnetic resonance spectroscopy and metabolite imaging
14. Serial proton MR spectroscopy of contrast-enhancing multiple sclerosis plaques: Absolute metabolic values over 2 years during a clinical pharmacological study
15. Estimation of metabolite concentrations from localized in vivo NMR spectra
16. Brain N-acetylaspartate is elevated in Pelizaeus-Merzbacher disease with PLP1 duplication
17. Acute hyperammonemia in the young primate: Physiologic and neuropathologic correlates
18. Cerebral blood flow and metabolism in chronically hyperammonemic rats: Effect of an acute ammonia challenge
19. Intracranial pressure, cerebral blood flow and cerebrospinal fluid formation during hyperammonemia in cat
20. Toxic and metabolic brain disorders
21. Regulation of cell volume in health and disease
22. Transient idiopathic hyperammonaemia in adults
23. Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats
24. Osmoregulatory changes in myo-inositol content and Na+/myo-inositol cotransport in rat cortical astrocytes