Cross-reactivity of anti-CagA antibodies with vascular wall antigens: Possible pathogenic link between Helicobacter pylori infection and atherosclerosis

Circulation

Volumn 106, Issue 4, 2002, Pages 430-434

  Franceschi, Francesco ^a   Sepulveda, Antonia R ^a   Gasbarrini, Antonio ^a   Pola, Paolo ^a   Silveri, Nicolò Gentiloni ^a   Gasbarrini, Giovanni ^a   Graham, David Y ^a   Genta, Robert M ^a  

^a MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Antibodies; Atherosclerosis; Infection

Indexed keywords

BUFFER; CAGA ANTIBODY; CAGA PROTEIN; POLYCLONAL ANTIBODY; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIGEN ANTIBODY REACTION; ARTICLE; ATHEROSCLEROSIS; CELL MEMBRANE; CELL NUCLEUS; CONTROLLED STUDY; CROSS REACTION; CYTOPLASM; DISEASE ASSOCIATION; ENDOTHELIUM CELL; FIBROBLAST; GASTROINTESTINAL TRACT; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INTIMA; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR; SMOOTH MUSCLE FIBER; UMBILICAL CORD;

ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; ARTERIES; ARTERIOSCLEROSIS; AUTOANTIGENS; BACTERIAL PROTEINS; CROSS REACTIONS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; PRECIPITIN TESTS;

EID: 0037162341     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000024100.90140.19     Document Type: Article

References (34)

1. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
2. Changing concepts of atherogenesis
3. The pathogenesis of atherosclerosis: A perspective for the 1990s
4. Epidemiological risk factors of coronary heart disease are not causal in atherosclerosis
5. How well can we predict coronary heart disease? Findings in the United Kingdom Heart Disease Prevention Project
6. Apolipoproteins and ischaemic heart disease: Implications for screening
7. Relationship of glucose intolerance to coronary risk in Afro-Carribeans compared with Europeans
8. The changing pattern of cardiovascular diseases in China
9. Autoimmunity and atherosclerosis
10. Immune and inflammatory mechanisms in the development of atherosclerosis
11. Atherosclerosis, inflammation and infection
12. The variable role of inflammation in acute coronary syndromes and in restenosis
13. Evidence of a chronic systemic cause of instability of atherosclerotic plaques
14. Autoimmunity in atherosclerosis: The role of autoantigens
15. Autoimmunity in atherosclerosis: Lessons from experimental models
16. Risk factors for coronary heart disease and infection with Helicobacter pylori: Meta-analysis of 18 studies
17. Helicobacter and atherosclerosis
18. Association of Helicobacter pylori infection with elevated serum lipids
19. Fibrinogen: A link between chronic infection and ischaemic heart disease
20. Treatment of Helicobacter pylori and Chlamydia pneumoniae infections decreases fibrinogen plasma level in patients with ischemic heart disease
21. Association between antibodies to heat shock protein 65 and coronary atherosclerosis: Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk
22. New acquisitions in Helicobacter pylori characteristics
23. Association of virulent Helicobacter pylori strains with ischemic heart disease
24. Immunomodulation of atherosclerosis: Myth and reality
25. Helicobacter pylori infection and mortality from ischaemic heart disease: Negative result from a large, prospective study
26. Association of Helicobacter pylori infection with lifestyle, chronic disease, body-indices, and age at menarche in Danish adults
27. Is there mimicry between arteriosclerotic lesions and H pylori antigens?
28. Detection of Chlamydia pneumoniae and Helicobacter pylori DNA in human atherosclerotic plaques by PCR
29. Detection of Helicobacter pylori in human carotid atherosclerotic plaques
30. Infectious agents in coronary lesions obtained by endatherectomy: Pattern of distribution, coinfection, and clinical findings
31. Interleukin-15 and its impact on neutrophil function
32. Transient induction of cytokine production in human myocardial fibroblasts by coxackievirus B3
33. RANTES production by cytokine-stimulated nasal fibroblasts: Its inhibition by glucocorticoids
34. Immunohistochemical detection of interferon-γ: Fake or fact?