Pyrazolopyrimidine-2,4-dione sulfonamides: Novel and selective calcitonin inducers

Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2002, Pages 2342-2345

  Gilbert, Adam M ^a   Caltabiano, Stephen ^b   Koehn, Frank E ^a   Chen, Zhen Jia ^a   Francisco, Gerardo D ^a   Ellingboe, John W ^a   Kharode, Yogendra ^b   Mangine, AnnaMarie ^b   Francis, Rita ^b   TrailSmith, Mark ^b   Gralnick, David ^b  

^a WYETH RESEARCH   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,6 DIBUTYL 2 METHANESULFONYL 2,4 DIHYDROPYRAZOLO[4,3 D]PYRIMIDINE 5,7 DIONE; 4,7 DIBUTYL 2 METHANESULFONYL 2,7 DIHYDROPYRAZOLO[3,4 D]PYRIMIDINE 4,6 DIONE; CALCITONIN; DENBUFYLLENE; LUCIFERASE; PHOSPHODIESTERASE INHIBITOR; PYRAZOLOPYRIMIDINE DERIVATIVE; SULFONAMIDE; UNCLASSIFIED DRUG; XANTHENE DERIVATIVE;

ARTICLE; BONE ATROPHY; CONCENTRATION RESPONSE; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HORMONE RELEASE; HORMONE SYNTHESIS; PROMOTER REGION; PROTEIN INDUCTION; RADIOIMMUNOASSAY; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; CALCITONIN; CELL LINE; GENES, REPORTER; HUMANS; LUCIFERASES; PHOSPHODIESTERASE INHIBITORS; PYRIMIDINES; RADIOIMMUNOASSAY; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TRANS-ACTIVATION (GENETICS); XANTHINES;

EID: 0037161577     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010554s     Document Type: Article

References (15)

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