Synthesis and reactions of enantiopure 1-acyl-2-[triaryl(alkyl)silyl]-2,3-dihydro-4-pyridones

Heterocycles

Volumn 58, Issue , 2002, Pages 505-519

  Comins, Daniel L ^a   Killpack, Michael O ^b   Despagnet, Emilie ^a   Zeller, Emmanuel ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b UTAH STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 4 PYRIDONE; 4 PYRIDONE DERIVATIVE; HETEROCYCLIC COMPOUND; PYRIDINIUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHIRALITY; CONFORMATIONAL TRANSITION; ENANTIOMER; REACTION ANALYSIS; REDUCTION; STEREOCHEMISTRY; SYNTHESIS;

EID: 0037159716     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-02-s(m)46     Document Type: Article

References (20)

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2. nd Ed. by A. McKillop, Pergamon Press, Oxford England, 1996, Vol. 5, pp. 37-89.
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7. D. L. Comins and J. M. Salvador, J. Org. Chem., 1993, 58, 4656.
8. For preliminary results, see: D. L. Comins and M. O. Killpack, J. Am. Chem. Soc., 1992, 114, 10972.
9. 3SiLi. For the preparation of the lithium reagent, see: M. V. George, D. J. Peterson, and H. Gilman, J. Am. Chem. Soc., 1960, 82, 403.
10. D. L. Comins and D. H. LaMunyon, Tetrahedron Lett., 1988, 29, 773.
11. P. Singh, D. L.Comins, and M. O. Killpack, Acta Crystallogr., 1990, C46, 1955.
12. 2, see reference 5.
13. Molecular modeling program: MacSPARTAN Pro (1.04) by Wavefunction, Inc. Force field, MMFF (conformer distribution).
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16. R. W. Hoffman, Chem. Rev., 1989, 89, 1841; F. Johnson, Chem. Rev., 1968, 68, 375; M. A. Foley and D. L. Comins, J. Am. Chem. Soc., 1988, 110, 7445 and references cited therein.
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20. D. L. Comins, G. Chung, and M. A. Foley, Heterocycles, 1994, 37, 1121.