Synthesis and structure-activity relationships of a novel series of HIV-1 protease inhibitors encompassing ABT-378 (Lopinavir)

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 8, 2002, Pages 1185-1187

  Sham, Hing L ^a   Betebenner, David A ^a   Chen, Xiaoqi ^a   Saldivar, Ayda ^a   Vasavanonda, Sudthida ^a   Kempf, Dale J ^a   Plattner, Jacob J ^a   Norbeck, Daniel W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DERIVATIVE; LOPINAVIR; PROTEINASE INHIBITOR;

ARTICLE; CHEMICAL STRUCTURE; DERIVATIZATION; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

CELL LINE; HIV PROTEASE INHIBITORS; HUMANS; PYRIMIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037156354     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00134-8     Document Type: Article

References (9)