A 32-year-old man with hemoptysis of nearly three decades' duration

New England Journal of Medicine

Volumn 347, Issue 21, 2002, Pages 1693-1701

  Silverman, E S ^a   Mark, E J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; AZITHROMYCIN; COTRIMOXAZOLE; LEVOFLOXACIN; NEUTROPHIL CYTOPLASMIC ANTIBODY; PNEUMOCOCCUS VACCINE; PREDNISONE; SALBUTAMOL; SULFAFURAZOLE;

ADULT; ANAMNESIS; ARTICLE; ASTHMA; BRONCHIOLITIS; BRONCHITIS; CASE REPORT; CHRONIC DISEASE; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; COUGHING; CROUP; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; DYSPNEA; FOLLOW UP; HEMATOCHEZIA; HEMOPTYSIS; HOSPITAL ADMISSION; HUMAN; INTERSTITIAL LUNG DISEASE; IRON DEFICIENCY ANEMIA; KETONURIA; LACTOSE INTOLERANCE; LUNG BIOPSY; LUNG FUNCTION TEST; LUNG HEMORRHAGE; LUNG HEMOSIDEROSIS; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREGNANCY COMPLICATION; PRIORITY JOURNAL; SPUTUM CULTURE; THORAX RADIOGRAPHY; URINARY TRACT INFECTION; BLOOD; CLINICAL OBSERVATION; CLINICAL STUDY; DIAGNOSIS; HEMOSIDEROSIS; LUNG; LUNG DISEASE; PATHOLOGY; RADIOGRAPHY; WEGENER GRANULOMATOSIS;

ADULT; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; DIAGNOSIS, DIFFERENTIAL; DYSPNEA; HEMOPTYSIS; HEMOSIDEROSIS; HUMANS; LUNG; LUNG DISEASES; LUNG DISEASES, INTERSTITIAL; MALE; WEGENER GRANULOMATOSIS;

EID: 0037153039     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMcpc020020     Document Type: Article

References (39)

1. Hirshberg B, Biran I, Glazer M, Kramer MR. Hemoptysis: Etiology, evaluation, and outcome in a tertiary referral hospital. Chest 1997;112:440-4.
2. Balter MS. Hemoptysis. In: Irwin RS, Curley FJ, Grossman RF, eds. Diagnosis and Treatment of Symptoms of the Respiratory Tract. Armonk, N.Y.: Futura Publishing, 1997:155-97.
3. Specks U. Diffuse alveolar hemorrhage syndromes. Curr Opin Rheumatol 2001;13:12-7.
4. Naidich DP, Funt S, Ettenger NA, Arranda C. Hemoptysis: CT-bronchoscopic correlations in 58 cases. Radiology 1990;177:357-62.
5. Travis WD, Colby TV, Lombard C, Carpenter HA. A clinicopathologic study of 34 cases of diffuse pulmonary hemorrhage with lung biopsy confirmation. Am J Surg Pathol 1990;14:1112-25.
6. Thomas HM III, Irwin RS. Classification of diffuse intrapulmonary hemorrhage. Chest 1975;68:483-4.
7. Ewan PW, Jones HA, Rhodes CG, Hughes JMB. Detection of intrapulmonary hemorrhage with carbon monoxide uptake: Application in Goodpasture's syndrome. N Engl J Med 1976;295:1391-6.
8. Capron F. Pulmonary hemorrhage syndromes. In: Hasleton P, ed. Spencer's Pathology of the Lung. 5th Ed. New York: McGraw-Hill, 1996:865-74.
9. Britton R, Tavill A, Bacon B. Mechanisms of iron toxicity. In: Brock J, Halliday J, Pippard M, Powell L, eds. Iron Metabolism in Health and Disease. London: W.B. Saunders, 1994:317-51.
10. Hoffman GS, Kerr GS, Leavitt RY, et al. Wegener granulomatosis: An analysis of 158 patients. Ann Intern Med 1992;116:488-98.
11. Ball JA, Young KR Jr. Pulmonary manifestations of Goodpasture's syndrome: Antiglomerular basement membrane disease and related disorders. Clin Chest Med 1998;19:777-91.
12. Zamora MR, Warner ML, Tuder R, Schwarz MI. Diffuse alveolar hemorrhage and systemic lupus erythematosus: Clinical presentation, histology, survival, and outcome. Medicine (Baltimore) 1997;76:192-202.
13. Homer R. Antineutrophil cytoplasmic antibodies as markers for systemic autoimmune disease. Clin Chest Med 1998;19:627-39.
14. Guillevin L, Durand-Gasselin B, Cevallos R, et al. Microscopic polyangiitis: Clinical and laboratory findings in eighty-five patients. Arthritis Rheum 1999;42:421-30.
15. Wilson CB, Dixon FJ. Anti-glomerular basement membrane antibody-induced glomerulonephritis. Kidney Int 1973;3:74-89.
16. Evans J. Antinuclear antibody testing in systemic autoimmune disease. Clin Chest Med 1998;19:613-25.
17. Tan E. Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology. Adv Immunol 1989;44:93-151.
18. Fossati G, Perri M, Careddu G, Mirra N, Carnelli V. Emosiderosi polmonare indotta dalle proteine del latte vaccino: Discussione di un caso clinico. Pediatr Med Chir 1992;14:203-7
19. Gertner E. Diffuse alveolar hemorrhage in the antiphospholipid syndrome: Spectrum of disease and treatment. J Rheumatol 1999;26:805-7
20. Mark EJ, Matsubara O, Tan-Liu NS, Fienberg R. The pulmonary biopsy in the early diagnosis of Wegener's (pathergic) granulomatosis: A study based on 35 open lung biopsies. Hum Pathol 1988;19:1065-71.
21. Mark EJ, Ramirez JF. Pulmonary capillaritis and hemorrhage in patients with systemic vasculitis. Arch Pathol Lab Med 1985;109:413-8.
22. Jennings CA, King TE Jr, Tuder R, Cherniack RM, Schwarz MI. Diffuse alveolar hemorrhage with underlying isolated, pauciimmune pulmonary capillaritis. Am J Respir Crit Care Med 1997;155:1101-9.
23. Milman N, Pedersen FM. Idiopathic pulmonary haemosiderosis: Epidemiology, pathogenic aspects and diagnosis. Respir Med 1998;92:902-7.
24. Kjellman B, Elinder G, Garwicz S, Svan H. Idiopathic pulmonary haemosiderosis in Swedish children. Acta Paediatr Scand 1984;73:584-8.
25. Ohga S, Takahashi K, Miyazaki S, Kato H, Ueda K. Idiopathic pulmonary haemosiderosis in Japan: 39 Possible cases from a survey questionnaire. Eur J Pediatr 1995;154:994-5.
26. Bronson SM. Idiopathic pulmonary hemosiderosis in adults: Report of a case and review of the literature. AJR Am J Roentgenol 1960;83:260-73.
27. Morgan PG, Turner-Warwick M. Pulmonary haemosiderosis and pulmonary haemorrhage. Br J Dis Chest 1981;75:225-42.
28. Thaell JF, Greipp PR, Stubbs SE, Siegal GP. Idiopathic pulmonary hemosiderosis: Two cases in a family. Mayo Clin Proc 1978;53:113-8.
29. Cassimos CD, Chryssanthopoulos C, Panagiotidou C. Epidemiologic observations in idiopathic pulmonary hemosiderosis. J Pediatr 1983;102:698-702.
30. Wright PH, Menzies IS, Pounder RE, Keeling PW. Adult idiopathic pulmonary haemosiderosis and coeliac disease. Q J Med 1981;197:95-102.
31. Reading R, Watson JG, Platt JW, Bird AG. Pulmonary haemosiderosis and gluten. Arch Dis Child 1987;62:513-5.
32. Pacheco A, Casanova C, Fogue L, Sueiro A. Long-term clinical follow-up of adult idiopathic pulmonary hemosiderosis and celiac disease. Chest 1991;99:1525-6.
33. Soergel KH, Sommers SC. Idiopathic pulmonary hemosiderosis and related syndromes. Am J Med 1962;32:499-511.
34. Saeed MM, Woo MS, MacLaughlin EF, Margetis MF, Keens TG. Prognosis in pediatric idiopathic pulmonary hemosiderosis. Chest 1999;116:721-5.
35. Kiper N, Gocmen A, Ozcelik U, Dilber E, Anadol D. Long-term clinical course of patients with idiopathic pulmonary hemosiderosis (1979-1994): Prolonged survival with low-dose corticosteroid therapy. Pediatr Pulmonol 1999;27:180-4.
36. Rossi G, Balzano E, Battistini E, et al. Long-term prednisone and azathioprine treatment of a patient with idiopathic pulmonary hemosiderosis. Pediatr Pulmonol 1992;13:176-80.
37. Mandel J, Mark EJ, Hales CA. Pulmonary veno-occlusive disease. Am J Respir Crit Care Med 2000;162:1964-73.
38. Letrieri C, Pina J. Goodpasture's syndrome: A case of delayed appearance of autoantibodies and renal disease. Mil Med 2001;166:827-30.
39. Case Records of the Massachusetts General Hospital (Case 52-1993). N Engl J Med 1993;329:2019-26.