Cellular actions of Al at low (1.25 μM) concentrations in primary oligodendrocyte culture

Brain Research

Volumn 941, Issue 1-2, 2002, Pages 82-90

  Golub, Mari S ^a   Zhang, Wei ^a   Keen, Carl L ^a   Goldkorn, Tzipora ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aluminum; Cell culture; Oligodendrocyte; Oxidative damage; Protein synthesis; Signal transduction

Indexed keywords

ALUMINUM; ALUMINUM CHLORIDE; ALUMINUM DERIVATIVE; ALUMINUM TRANSFERRIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL TRISPHOSPHATE; LACTATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; LIPID PEROXIDATION; NEWBORN; NONHUMAN; OLIGODENDROGLIA; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; RNA SYNTHESIS; SIGNAL TRANSDUCTION;

ALUMINUM; ALUMINUM COMPOUNDS; ANIMALS; APOPROTEINS; CELL CULTURE TECHNIQUES; CHLORIDES; LIPID PEROXIDATION; OLIGODENDROGLIA; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; RATS; REACTIVE OXYGEN SPECIES; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; TRANSFERRIN;

EID: 0037150799     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)02597-0     Document Type: Article

References (43)

1. Brain neurons develop in a serum and glial free environment: Effects of transferrin, insulin, insulin-like growth factor-I and thyroid hormone on neuronal survival, growth and differentiation
2. Aluminum neurotoxicity in preterm infants receiving intravenous-feeding solutions
3. Aluminum but not iron treatment induces pro-oxidant events in the rat brain
4. Aluminum-induced oxidative events in cell lines: Glioma are more responsive than neuroblastoma
5. + channels
6. Extracellular calcium-sensing receptor induces cellular proliferation and activation of a nonselective cation channel in U373 human astrocytoma cells
7. Alternative splicing prevents transferrin secretion during differentiation of a human oligodendrocyte cell line
8. Long term consequences of developmental exposure to aluminum in a suboptimal diet for growth and behavior of Swiss Webster mice
9. Effects of aluminum on transferrin mediated iron uptake in primary cultures of rat neurons, astrocytes and oligodendrocytes
10. Morphometric studies of myelination in the spinal cord of mice exposed developmentally to aluminum
11. What we know and what we need to know about developmental aluminum toxicity
12. Aluminum effects on operant performance and food motivation of mice
13. Aluminum uptake and effects on transferrin mediated iron uptake in primary cultures of rat neurons, astrocytes and oligodendrocytes
14. Behavioral performance of Swiss Webster mice exposed to excess dietary aluminum during development or during development and as adults
15. Neurodevelopmental effect of aluminum in mice: Fostering studies
16. Adjuvant properties of aluminum and calcium compounds
17. Aluminium salts accelerate peroxidation of membrane lipids stimulated by iron salts
18. Speciation of aluminum in biological systems
19. Aluminum potentiates Pi transport stimulation induced by fluoride in osteoblast-like cells
20. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury
21. Systemic aluminum toxicity: Effects on bone, hematopoietic tissue, and kidney
22. Complementary metal ion specificity of the metal citrate transporters CitM and CitH of Bacillus subtilis
23. Aluminum stimulates the proliferation and differentiation of osteoblasts in vitro by a mechanism that is different from fluoride
24. CG-4, a new bipotential glial cell line from rat brain, is capable of differentiating in vitro into either mature oligodendrocytes or type-2 astrocytes
25. Aluminum enhances melanin-induced lipid peroxidation
26. Transferrin and transferrin receptor function in brain barrier systems
27. Health effects of aluminum: A critical review with emphasis on aluminum in drinking water
28. A mechanism for the stimulatory effect of aluminum on iron-induced lipid peroxidation
29. Aluminum has both oxidant and antioxidant effects in mouse brain membranes
30. Aluminum accumulation and neurotoxicity in Swiss-Webster mice after long-term dietary exposure to aluminum and citrate
31. Sensing of extracellular cations in CasR-deficient osteoblasts: Evidence for a novel cation-sensing mechanism
32. Aluminum-induced mitogenesis in MC3T3-E1 osteoblasts: Potential mechanism underlying neo-osteogenesis
33. Effects of aluminum on neuronal signal transduction: Mechanisms underlying disruption of phosphoinositide hydrolysis
34. Aluminum is a weak agonist for the calcium-sensing receptor
35. Effects of various metals on DNA synthesis and lymphokines production by human peripheral blood lymphocytes in vitro
36. Effect of trivalent metal ions on phase separation and membrane lipid packing: Role in lipid peroxidation
37. 2+ initiated lipid peroxidation
38. Myelin is a preferential target of aluminum-mediated oxidative damage
39. 3+-mediated lipid oxidation. Effect of galactolipids
40. Effect of aluminum chloride on mitogenesis, mitosis and cell cycle in human short-term whole blood cultures: Lower concentrations enhance mitosis
41. The toxicology of aluminum in the brain: A review
42. The distribution of aluminum into and out of the brain
43. An improved method for propagating oligodendrocyte progenitors in vitro