A sequence repeat in the insulin-like growth factor-1 gene and risk of breast cancer

International Journal of Cancer

Volumn 100, Issue 3, 2002, Pages 332-336

  Missmer, Stacey A ^a,b   Haiman, Christopher A ^a,b,d   Hunter, David J ^a,b,c   Willett, Walter C ^a,b,c   Colditz, Graham A ^a,b,c   Speizer, Frank E ^a   Pollak, Michael N ^e   Hankinson, Susan E ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c HARVARD CENTER FOR CANCER PREVENTION   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

Breast cancer; Epidemiology; Insulin like growth factor 1 polymorphism

Indexed keywords

SOMATOMEDIN C;

ADULT; AGED; ALLELE; ARTICLE; BREAST CANCER; CANCER RISK; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MENOPAUSE; POSTMENOPAUSE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ADULT; BREAST NEOPLASMS; FEMALE; GENOTYPE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MIDDLE AGED; REPETITIVE SEQUENCES, NUCLEIC ACID; RISK;

EID: 0037143088     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10473     Document Type: Article

References (29)

1. Insulin-like growth factors/somatomedins: Structure, secretion, biological actions, and physiological role
2. Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice
3. Intact and amino-terminally shortened forms of insulin-like growth factor I induce mammary gland differentiation and development
4. Insulin-like growth factors and their binding proteins: Biological actions
5. Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation
6. Growth hormone treatment induces mammary gland hyperplasia in aging primates
7. Insulin-like growth factor-binding proteins in serum and other biological fluids: Regulation and functions
8. IGF physiology and cancer risk
9. Serum insulin-like growth factor I in 1030 healthy children, adolescents, and adults: Relation to age, sex, stage of puberty, testicular size, and body mass index
10. Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: The relation to IGF-I, IGF-II, IGFBP-I, IGFBP-2, age, sex, body mass index and pubertal maturation
11. Insulin-like growth factor binding protein 3 is decreased in early-stage operable premenopausal breast cancer
12. Circulating concentrations of insulin-like growth factor-1 and risk of breast cancer
13. Insulin-like growth factor-I in relation to premenopausal ductal carcinoma in situ of the breast
14. Serum insulin-like growth factor-I and breast cancer
15. Genetic and environmental components of interindividual variation in circulating levels of IGF-I, IGF-II, IGFBP-1, and IGFBP-3
16. Organization and sequence of the human IGF-I gene
17. Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction
18. Expression of IGF-I mRNA variants in rat bone
19. 17 β estradiol potentially suppresses cAMP-induced IGF-I gene activation in primary rat osteoblasts cultures
20. Association between serum insulin growth factor-1 (IGF-1) and a simple sequence repeat in IGF-1 gene: Implications for genetic studies of bone mineral density
21. Genetic factors related to racial variation in plasma levels of insulin-like growth factor-1: Implications for pre-menopausal breast cancer risk
22. A polymorphism in the gene for IGF-1: Functional properties and risk for type 2 diabetes and myocardial infarction
23. Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women
24. Differential effects of oral conjugated estrogens and transdermal estradiol on insulin-like growth factor I, growth hormone and sex hormone binding globulin serum levels
25. Cigarette smoking, cytochrome P450 1A1 polymorphisms, and breast cancer risk in the Nurses' Health Study
26. Plasma IGF-I concentrations in human breast cancer
27. Insulin-like growth factor-1 and breast cancer risk in postmenopausal African-American women
28. Insulin and related factors in premenopausal breast cancer risk
29. Leptin and insulin growth factor I in relation to breast cancer