Continuous pH monitoring in a perfused bioreactor system using an optical pH sensor

Biotechnology and Bioengineering

Volumn 78, Issue 4, 2002, Pages 467-472

  Jeevarajan, Antony S ^a   Vani, Sundeep ^b   Taylor, Thomas D ^a   Anderson, Melody M ^c  

^a WYLE LABORATORIES   (United States)

^b MONSANTO COMPANY   (United States)

^c NASA JOHNSON SPACE CENTER   (United States)

Author keywords

Cell culture; Non invasive; Optical sensor; pH; Phenol red

Indexed keywords

BIOSENSORS; BLOOD GAS ANALYSIS; CALIBRATION; CELL CULTURE; LIGHT ABSORPTION; OPTICAL SENSORS; PH EFFECTS; SPECTROPHOTOMETERS;

PERFUSED BIOREACTOR SYSTEMS;

BIOREACTORS;

PHENOLSULFONPHTHALEIN;

ANIMAL CELL; ARTICLE; BIOFILM; BIOPROCESS; BIOREACTOR; BLOOD GAS ANALYSIS; CELL CULTURE; CONTROLLED STUDY; FIBER OPTIC BIOSENSOR; HAMSTER; KIDNEY CELL; LIGHT ABSORPTION; NONHUMAN; OPTICAL BIOSENSOR; PH MEASUREMENT; SPECTROPHOTOMETRY;

ANIMALS; BIOFILMS; BIOREACTORS; CELL LINE; CRICETINAE; CULTURE MEDIA; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEASIBILITY STUDIES; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; KIDNEY; MEMBRANE GLYCOPROTEINS; OPTICS; PERFUSION; PHENOLSULFONPHTHALEIN; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY; TIME FACTORS; TRANSDUCERS; UNITED STATES; UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION;

CRICETINAE;

EID: 0037141579     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10212     Document Type: Article

References (17)

1. Factors affecting the response time of an optical-fibre reflectance pH sensor
2. In vivo optical-fibre pH sensor for gastro-oesophageal measurements
3. Simple fiber optic spectrophotometric cell for pH determination
4. Evaluation of a luminescent ruthenium complex immobilized inside Nafion as optical pH sensor
5. Optical-fibre pH sensor
6. Luminescence and charge transfer. Part 3. The use of chromophores with ICT (internal charge transfer) excited states in the construction of fluorescent PET (photoinduced electron transfer) pH sensors and related absorption pH sensors with aminoalkyl side chains
7. Sol-gel based fiber optic pH sensor
8. Experimental results on an optical pH measurement system for bioreactors
9. Protein binding of small molecules II. Role of electrostatic forces for binding of phenol red by human serum albumin
10. Fiber optic pH probe for physiological use
11. Spectrophotometric determination of seawater pH using phenol red
12. In vivo spectroscopic properties of the fluorescent pH indicator biscarboxyethyl carboxyfluorescein
13. Optically transparent polyelectrolyte-silica composite materials: Preparation, characterization and application in optical chemical sensing
14. Coumarin-4-doped sol-gel coating film as optical pH sensor
15. Phenol red inhibits growth of renal epithelial cells
16. Optical triple sensor for measuring pH, oxygen and carbon dioxide
17. Investigation of an optical fibre pH sensor with the membrane based on phospholipid copolymer