Transcriptional analysis of the major antigenic protein 1 multigene family of Cowdria ruminantium

Gene

Volumn 285, Issue 1-2, 2002, Pages 193-201

  Bekker, Cornelis P J ^a   Bell Sakyi, Lesley ^b   Paxton, Edith A ^b   Martinez, Dominique ^c   Bensaid, Albert ^c   Jongejan, Frans ^a,d  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c CIRAD   (France)

^d UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

Amblyomma variegatum; Differential transcription; Tick cell lines; Ticks

Indexed keywords

INSECT PROTEIN; ISOPROTEIN; MAJOR ANTIGENIC PROTEIN 1; UNCLASSIFIED DRUG;

AMBLYOMMA; ANIMAL CELL; ARTICLE; CATTLE; CELL GROWTH; CELL LINE; CONTROLLED STUDY; EHRLICHIA; ENDOTHELIUM CELL; GENE ISOLATION; GENE LOCUS; GENE SEQUENCE; GENETIC TRANSCRIPTION; IN VITRO STUDY; INSECT GENETICS; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; TEMPERATURE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; CATTLE; CELL LINE; CELLS, CULTURED; CLONING, MOLECULAR; DNA, BACTERIAL; EHRLICHIA RUMINANTIUM; ENDOTHELIUM, VASCULAR; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; RNA, BACTERIAL; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TICKS; TRANSCRIPTION, GENETIC;

ACARI; AMBLYOMMA; AMBLYOMMA VARIEGATUM; BOVINAE; EHRLICHIA; EHRLICHIA RUMINANTIUM;

EID: 0037138412     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(02)00408-0     Document Type: Article

References (27)

1. The carrier status of sheep, cattle and African buffalo recovered from heartwater
2. Growth of Cowdria ruminantium, the causative agent of heartwater, in a tick cell line
3. Cowdria ruminantium DNA is unstable in a SuperCos1 library
4. Sequential evaluation of dogs naturally infected with Ehrlichia canis, Ehrlichia chaffeensis, Ehrlichia equi, Ehrlichia ewingii, or Bartonella vinsonii
5. Anaplasma marginale: Detection of carrier cattle by PCR-ELISA
6. Protective immunity to heartwater (Cowdria ruminantium infection) is acquired after vaccination with in vitro-attenuated rickettsiae
7. Outer membrane protein-specific monoclonal antibodies protect SCID mice from fatal infection by the obligate intracellular bacterial pathogen Ehrlichia chaffeensis
8. Molecular cloning of the gene for a conserved major immunoreactive 28-kDa protein of Ehrlichia canis: A potential serodiagnostic antigen
9. A conserved, transcriptionally active p28 multigene locus of Ehrlichia canis
10. A DNA vaccine protects mice against the rickettsial agent Cowdria ruminantium
11. Cloning and characterization of multigenes encoding the immunodominant 30-kDa major outer membrane proteins of Ehrlichia canis and application of the recombinant protein for serodiagnosis
12. Immunodominant major outer membrane proteins of Ehrlichia chaffeensis are encoded by a polymorphic multigene family
13. Analysis of transcriptionally active gene clusters of major outer membrane protein multigene family in Ehrlichia canis and E. chaffeensis
14. The immunoprotective Anaplasma marginale major surface protein 2 is encoded by a polymorphic multigene family
15. Persistence of Anaplasma ovis infection and conservation of the msp-2 and msp-3 multigene families within the genus Anaplasma
16. Sequence heterogeneity of the major antigenic protein 1 genes from Cowdria ruminantium isolates from different geographical areas
17. Molecular characterization of a 28 kDa surface antigen gene family of the tribe Ehrlichiae
18. Western immunoblot analysis of Ehrlichia chaffeensis, E. canis, or E. ewingii infections in dogs and humans
19. Identification of the antigenic proteins of Cowdria ruminantium
20. Restriction of major surface protein 2 (MSP2) variants during tick transmission of the ehrlichia Anaplasma marginale
21. The map1 gene of Cowdria ruminantium is a member of a multigene family containing both conserved and variable genes
22. Heartwater (Cowdria ruminantium infection): Current status
23. Phylogenetic position of Cowdria ruminantium (Rickettsiales) determined by analysis of amplified 16S ribosomal DNA sequences
24. Molecular cloning, sequence analysis, and expression of the gene encoding the immunodominant 32-kDa protein of Cowdria ruminantium
25. Detection of Ehrlichia chaffeensis in human tissue by using a species-specific monoclonal antibody
26. Genetic diversity of the 28-kDa outer membrane protein gene in human isolates of Ehrlichia chaffeensis
27. Characterization of the complete transcriptionally active Ehrlichia chaffeensis 28 kDa outer membrane protein multigene family