In silico and NMR identification of inhibitors of the IGF-I and IGF-binding protein-5 interaction

Journal of Medicinal Chemistry

Volumn 45, Issue 26, 2002, Pages 5655-5660

  Kamionka, Mariusz ^a,c   Rehm, Till ^a   Beisel, Hans Georg ^a   Lang, Kurt ^b   Engh, Richard A ^b   Holak, Tad A ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; HYDROGEN BOND; LIGAND BINDING; MOLECULAR MODEL; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE MAPPING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

AMINO ACIDS; BINDING SITES; FLUORENES; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5; INSULIN-LIKE GROWTH FACTOR I; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037137601     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0208828     Document Type: Article

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