Formaldehyde-induced DNA cross-link of indolizino[1,2-b]quinolines derived from the A-D rings of camptothecin

Journal of Medicinal Chemistry

Volumn 45, Issue 26, 2002, Pages 5809-5812

  Perzyna, Aurore ^a   Marty, Carine ^b   Facompré, Michael ^b   Goossens, Jean François ^a   Pommery, Nicole ^a   Colson, Pierre ^c   Houssier, Claude ^c   Houssin, Raymond ^a   Hénichart, Jean Pierre ^a   Bailly, Christian ^b  

^a Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

^b INSERM   (France)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

7 METHYL 9 OXO 1 (2 PIPERIDIN 1 YLETHOXY) 9,11 DIHYDROINDOLIZINO[1,2 B]QUINOLINE 8 CARBOXAMIDE; 7 METHYL 9 OXO 3 (2 PIPERIDIN 1 YLETHOXY) 9,11 DIHYDROINDOLIZINO[1,2 B]QUINOLINE 8 CARBOXAMIDE; 8 AMINOMETHYL 7 METHYL 9 OXO 2 (2 PIPERIDIN 1 YLETHOXY) 9,11 DIHYDROINDOLIZINO[1,2 B]QUINOLINE DIHYDROCHLORIDE; 8 AMINOMETHYL 7 METHYL 9 OXO 3 (2 PIPERIDIN 1 YLETHOXY) 9,11 DIHYDROINDOLIZINO[1,2 B]QUINOLINE DIHYDROCHLORIDE; 9,11 DIHYDROINDOLIZINO[1,2 B]QUINOLINE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN DERIVATIVE; DNA; INDOLIZINO[1,2 B]QUINOLINE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CROSS LINKING; DNA BINDING; DNA SEQUENCE; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING;

CAMPTOTHECIN; CROSS-LINKING REAGENTS; DEOXYRIBONUCLEASE I; DNA; DNA FOOTPRINTING; FORMALDEHYDE;

EID: 0037137597     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020235g     Document Type: Article

References (21)

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