Identification of arodyn, a novel acetylated dynorphin a-(1-11) analogue, as a κ opioid receptor antagonist

Journal of Medicinal Chemistry

Volumn 45, Issue 26, 2002, Pages 5617-5619

  Bennett, Marco A ^a   Murray, Thomas F ^b   Aldrich, Jane V ^c  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ARODYN; DYNORPHIN A [1-11] DERIVATIVE; DYNORPHIN A DERIVATIVE; DYNORPHIN[1-13]; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; NONHUMAN; RECEPTOR AFFINITY; RECEPTOR BLOCKING;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; DYNORPHINS; PEPTIDE FRAGMENTS; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, KAPPA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037137590     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm025575g     Document Type: Article

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25. + calcd 1534.9.