Pentylenetetrazol-kindling of seizures selectively decreases [3H]-citalopram binding in the CA-3 area of rat hippocampus

Neuroscience Letters

Volumn 335, Issue 1, 2002, Pages 49-53

  Szyndler, J ^a   Wierzba Bobrowicz, T ^b   Maciejak, P ^b   Siemiatkowski, M ^b   Rok, P ^b   Lehner, M ^b   Czlonkowska, A I ^a   Bidzinski, A ^b   Wislowska, A ^a   Zienowicz, M ^a   Plaznik, A ^a,b  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

Author keywords

3H citalopram; Autoradiography; Hippocampus; Immunocytochemistry; Kindling; Pentylenetetrazol; Rat

Indexed keywords

CITALOPRAM; PENTETRAZOLE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BRAIN REGION; CONTROLLED STUDY; DENTATE GYRUS; DRUG BINDING; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; KINDLING; MICROGLIA; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; REDUCTION; SEIZURE; SEROTONINERGIC NERVE CELL; STATISTICAL ANALYSIS;

ANIMALS; AUTORADIOGRAPHY; CARRIER PROTEINS; CITALOPRAM; CONVULSANTS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; KINDLING, NEUROLOGIC; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; PENTYLENETETRAZOLE; RATS; RATS, WISTAR; SEIZURES; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; TRITIUM;

EID: 0037137507     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)01141-2     Document Type: Article

References (20)

1. Abed W.T. The effect of monoamine depletors on metrazol induced convulsions and brain gamma-aminobutyric acid (GABA) contents in rats. J. Pharm. Pharmacol. 41:1989;807-808.
2. Aronica E., van Vliet E.A., Mayboroda O.A., Troost D., da Silva F.H., Gorter J.A. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. Eur. J. Neurosci. 12:(7):2000;2333-2344.
3. Becker A., Grecksch G., Thiemann W., Hollt V. Pentylenetetrazol-kindling modulates stimulated dopamine release in the nucleus accumbens of rats. Pharmacol. Biochem. Behav. 66:(2):2000;425-428.
4. Carrasco J., Penkova M., Hadberg H., Molinero A., Hidalgo J. Enhanced seizures and hippocampal neurodegeneration following kainic acid-induced seizures in metallothionein-I and II-deficient mice. Eur. J. Neurosci. 12:(7):2000;2311-2322.
5. Clark M., Weiss S.R.B., Post R.M. Autoradiographic analysis of serotonin receptors and transporter in kindled rat brain. Neurosci. Lett. 161:1993;21-26.
6. Franke H., Kittner H. Morphological alterations of neurons and astrocytes and changes in emotional behavior in pentylenetetrazol- kindled rats. Pharmacol. Biochem. Behav. 70:(2-3):2001;291-303.
7. 2+-induced epileptiform activity in rat entorhinal cortex. Epilepsia. 43:(2):2002;205-206.
8. Goddard G.V., McIntyre D.C., Leech C.K. A permanent change in brain function resulting from daily electrical stimulation. Exp. Neurol. 25:(3):1969;295-330.
9. Goodnick P.J., Goldstein B.J. Selective serotonin reuptake inhibitors in affective disorders: I, basic pharmacology. J. Psychopharmacol. 12:(3):1998;S5-S20.
10. Grootendorst J., Mulder M., Haasdijk E., de Kloet E.R., Jaarsma D. Presence of apolipoprotein E immunoreactivity in degenerating neurons of mice is dependent on the severity of kainic acid-induced lesion. Brain Res. 868:(2):2000;165-167.
11. Kalynchuk L.E. Long-term amygdala kindling in rats as a model for the study of interictal emotional in temporal lobe epilepsy. Neurosci. Biobehav. Rev. 24:2000;691-704.
12. Kuhar M.J., Unnerstall J.R. Receptor autoradiography. Yamamura H.J., Enna S.J., Kuhar M.J. Methods in Neurotransmitter Receptor Analysis. 1990;177-218 Raven Press, New York.
13. Lu K.T., Gean P.W. Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation. Neuroscience. 86:(3):1998;729-737.
14. Okada M., Hirano T., Mizuno K., Kawata Y., Wada K., Mizuno K., Kondo T., Kaneko S. Biphasic effects of zonisamide on serotonergic system in rat hippocampus. Epilepsy Res. 34:(2-3):1999;187-197.
15. Okada M., Hirano T., Mizuno K., Kawata Y., Wada K., Murakami H., Kaneko S. Effects of carbamazepine on hippocampal serotonergic system. Epilepsy Res. 31:(3):1998;187-198.
16. Shouse N.M., Staba R.J., Ko P., Saquib S.F., Farber R.P. Monoamines and seizures: microdialysis findings in locus ceruleus and amygdala before and during amygdala kindling. Brain Res. 892:2001;176-192.
17. Schmitz D., Gloveli T., Empson R.M., Draguhn A., Heinemann U. Serotonin reduces synaptic excitation in the superficial medial entorhinal cortex of the rat via a presynaptic mechanism. J. Physiol. 508:1998;119-129.
18. Wada Y., Hasegawa H., Nakamura M., Yamaguchi N. Suppressive effects of L-5-hydroxytryptophan in a feline model of photosensitive epilepsy. Brain Res. 552:(1):1991;8-12.
19. Yan Q.S., Jobe P.C., Dailey J.W. Further evidence of anticonvulsant role of 5-hydroxytryptamine in genetically epilepsy-prone rats. Br. J. Pharmacol. 115:1993;977-985.
20. Zis A.P., Nomikos G.G., Brown E.E., Damsma G., Fibiger H.C. Neurochemical effects of electrically and chemically induced seizures: an in vivo microdialysis study in the rat hippocampus. Neuropsychopharmacology. 7:(3):1992;189-195.