Lipid peroxidation induced by phenylbutazone radicals

Life Sciences

Volumn 70, Issue 22, 2002, Pages 2611-2621

  Miura, Toshiaki ^a   Muraoka, Sanae ^a   Fujimoto, Yukio ^a  

^a HOKKAIDO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Horseradish peroxidase; Lipid peroxidation; Nonsteroidal anti inflammatory drug; Peroxyl radicals; Phenylbutazone radical

Indexed keywords

2 METHYL 2 NITROSOPROPAN; ARACHIDONIC ACID; CATALASE; DIMETHYL SULFOXIDE; GLUTATHIONE; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; MANNITOL; NITROSO DERIVATIVE; PEROXY RADICAL; PHENYLBUTAZONE; PHYCOERYTHRIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID;

ANIMAL CELL; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DECOMPOSITION; ELECTRON SPIN RESONANCE; LIPID PEROXIDATION; MICROSOME; NONHUMAN; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CATALASE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICAL SCAVENGERS; GLUTATHIONE; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MANNITOL; MICROSOMES, LIVER; OXIDATION-REDUCTION; PEROXIDES; PHENYLBUTAZONE; PHYCOERYTHRIN; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

ARMORACIA RUSTICANA;

EID: 0037134244     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)01554-0     Document Type: Article

References (32)

1. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
2. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
3. Non-steroidal anti-inflammatory drug gastropathy, causes and treatment
4. Structural requirements for the hepatotoxicity of nonsteroidal anti-inflammatory drugs in isolated rat hepatocytes
5. Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal anti-inflammatory drugs
6. Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats
7. Role of oxygen radical and lipid peroxidation in indomethacin-induced gastric mucosal injury
8. Lipid peroxidation in gastric mucosal lesions induced by indomethacin in rat
9. Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes
10. Prostaglandin hydroperoxidase, an integral part of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes
11. Purification and characterization of prostaglandin endoperoxide synthetase from sheep vesicular glands
12. Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation
13. Co-oxygenation of organic substrates by the prostaglandin synthetase of sheep vesicular gland
14. Mechanism of xenobiotic cooxygenation coupled to prostaglandin H2 biosynthesis
15. Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to cyclooxygenase activities
16. Non-steroidal anti-inflammatory agents and hepatic lipid peroxidation in normal-and carrageenin-treated rats
17. Promotion of oxidative damage to arachidonic acid and alpha 1-antiproteinase by anti-inflammatory drugs in the presence of the haem proteins myoglobin and cytochrome C
18. Oxidative damage to lipids and alpha 1-antiproteinase by phenylbutazone in the presence of haem proteins, protection by ascorbic acid
19. Phenylbutazone peroxidatic metabolism and conjugation
20. Phenylbutazone radicals inactivate creatine kinase
21. Inhibition of lipid peroxidation by estradiol and 2-hydroxyestradiol
22. Adaptation of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractions
23. Microsomal lipid peroxidation
24. Inhibition of microsomal lipid peroxidation by alpha-tocopherol and alpha-tocopherol acetate
25. Effects of alpha-phenyl N-tert-butylnitrone, a spin trap reagent, on the proliferation of murine hematopoietic progenitor cells in vitro
26. Phycoerythrin fluorescence-based assay for reactive oxygen species
27. Oxidation of thiol drugs and biochemicals by the lactoperoxidase/hydrogen peroxide system
28. Prostaglandin hydroperoxidase-dependent oxidation of phenylbutazone, relationship to inhibition of prostaglandin cyclooxygenase
29. Nonsteroidal antiinflammatory drugs interact with horseradish peroxidase in an in vitro assay system for hydrogen peroxide scavenging
30. Kinetic factors that control the fate of thiyl radicals in cells
31. Damage to biological tissues induced by radical initiator 2,2′-azobis(2-amidinopropane) dihydrochloride and its inhibition by chain-breaking antioxidants
32. Oxidative inactivation of gastric peroxidase by site-specific generation of hydroxyl radical and its role in stress-induced gastric ulceration