Ultrastructure of α-synuclein-positive aggregations in U373 astrocytoma and rat primary glial cells

Neuroscience Letters

Volumn 323, Issue 1, 2002, Pages 37-40

  Stefanova, N ^a   Emgard M ^b   Klimaschewski, L ^a   Wenning, G K ^a   Reindl, M ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Glia; Glial cytoplasmic inclusions; Lewy bodies; Neurodegeneration; Ultrastructure; Synuclein

Indexed keywords

ALPHA SYNUCLEIN;

ARTICLE; ASTROCYTE; ASTROCYTOMA; BIOLOGICAL MODEL; CARBOXY TERMINAL SEQUENCE; CELL ASSAY; CELL INCLUSION; CELL MEMBRANE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DEGENERATIVE DISEASE; GLIA CELL; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; OLIGODENDROGLIA; PATHOGENESIS; PRIORITY JOURNAL; STRUCTURE ANALYSIS; WILD TYPE;

EID: 0037134107     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00117-9     Document Type: Article

References (13)

1. Argyrophilic glial inclusions in the midbrain of patients with Parkinson's disease and diffuse Lewy body disease are immunopositive for NACP/alpha-synuclein
2. Synthetic filaments assembled from C-terminally truncated alpha-synuclein
3. Characterisation of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain
4. Alpha-synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components
5. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
6. α-Synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons
7. Alpha synuclein in neurodegenerative disorders: Murderer or accomplice
8. Cell death mechanisms in multiple system atrophy
9. Expression of α-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes associated with familial Parkinson's disease
10. Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies
11. Glial cell death induced by overexpression of alpha-synuclein
12. Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein
13. NACP/α-synuclein-positive inclusions in astrocytes and oligodendrocytes of Parkinson's disease brains