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Volumn 12, Issue 22, 2002, Pages 3267-3270

Facilely accessible multidrug resistance modulator derived from sucrose

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,3',4' O PENTAISOVALERYLSUCROSE; CARBOHYDRATE DERIVATIVE; GLYCOPROTEIN P; SUCROSE; UNCLASSIFIED DRUG; VERAPAMIL; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE;

EID: 0037131760     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00702-3     Document Type: Article
Times cited : (8)

References (14)
  • 10
    • 0005182249 scopus 로고    scopus 로고
    • note
    • 2), 50 μL solution of the anticancer agent (colchicine) and the testing sample was added to each well. Then, the whole mixture was further incubated for 48 h under the same condition as preincubation. The cytotoxic activity of the testing sample was also examined by MTT assay using parental KB-3-1 cells. Thereafter, 25 μL of MTT solution (2 mg/mL in PBS) was added to each well and incubated for further 3 h. After removing the medium by aspiration, the resulting formazan was extracted with 200 μL of dimethylsulfoxide. The percentage of cell growth inhibition was calculated from the absorbance at 540 nm.
  • 12
    • 0005225611 scopus 로고    scopus 로고
    • note
    • 16+Na: 785.3935: Found 785.3936.
  • 14
    • 0005230476 scopus 로고    scopus 로고
    • note
    • -3 μg/mL) exhibited no cytotoxicity against KB C-2. However, the 10 μg/mL concentration of 9 was cytotoxic against parental KB-3-1 cells ( Table 1 ). These findings might be ascribable to selective cytotoxic behavior of 9 against KB 3-1 cells similar to 1.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.