Capped dipeptide α-ketoacid inhibitors of the HCV NS3 protease

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 22, 2002, Pages 3325-3328

  Nizi, Emanuela ^a   Koch, Uwe ^a   Ponzi, Simona ^a   Matassa, Victor G ^a   Gardelli, Cristina ^a  

^a IRBM   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYACID; 2 OXOACID; DIPEPTIDE; MANDELIC ACID DERIVATIVE; MONTIRELIN; OXOACID; PROTEIN INHIBITOR; PROTEINASE; VIRUS PROTEIN; ENZYME INHIBITOR; NS3 PROTEIN, HEPATITIS C VIRUS;

ARTICLE; CAPPING PHENOMENON; HEPATITIS C VIRUS; HUMAN; IC 50; LIPOPHILICITY; MOLECULAR MODEL; PROTEIN SYNTHESIS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; HYDROGEN BOND; HYDROPHOBICITY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

HEPATITIS C VIRUS;

BINDING SITES; DIPEPTIDES; ENZYME INHIBITORS; HYDROGEN BONDING; HYDROPHOBICITY; INHIBITORY CONCENTRATION 50; KETO ACIDS; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0037131744     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00691-1     Document Type: Article

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