Cell-free biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya

Angewandte Chemie - International Edition

Volumn 41, Issue 20, 2002, Pages 3913-3915

  Schaffrath, Christoph ^a   Cobb, Steven L ^a   O'Hagan, David ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Biosynthesis; Biotransformations; Enzymes; Fluorine

Indexed keywords

ALDEHYDES; BIOSYNTHESIS; CELLS; METABOLITES;

INCUBATION;

FLUORINE COMPOUNDS;

5' DEOXY 5' FLUOROADENOSINE; ACETALDEHYDE; CELL EXTRACT; DEOXYADENOSINE DERIVATIVE; FLUORIDE; METHIONINE DERIVATIVE; ORGANOFLUORINE DERIVATIVE; UNCLASSIFIED DRUG; 2' DEOXY 2' FLUOROADENOSINE; 2'-FLUORO-2'-DEOXYADENOSINE; 4 FLUOROTHREONINE; 4-FLUOROTHREONINE; DRUG DERIVATIVE; FLUOROACETIC ACID; THREONINE;

ARTICLE; BIOSYNTHESIS; EXTRACTION; NONHUMAN; REACTION ANALYSIS; STREPTOMYCES; STREPTOMYCES CATTLEYA; BIOTRANSFORMATION; CELL FREE SYSTEM; ENZYMOLOGY; METABOLISM; SYNTHESIS;

BIOTRANSFORMATION; CELL-FREE SYSTEM; DEOXYADENOSINES; FLUORIDES; FLUOROACETATES; STREPTOMYCES; THREONINE;

EID: 0037131490     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3773(20021018)41:20<3913::AID-ANIE3913>3.0.CO;2-E     Document Type: Article

References (13)

1. D. B. Harper, D. O'Hagan, Nat. Prod. Rep. 1994, 123-133.
2. M. Sanada, T. Miyano, S. Iwadare, J. M. Williamson, B. H. Arison, J. L. Smith, A. W. Douglas, J. M. Liesch, E. Inamine, J. Antibiot. 1984, 39, 259-265.
3. K. A. Reid, J. T. G. Hamilton, R. D. Bowden, D. O'Hagan, L. Dasaradhi, M.R. Amin, D.B. Harper, Microbiology 1995, 141, 1385-1393.
4. D. O'Hagan, C. Schaffrath, S. Cobb, J. T. G. Hamilton, C. D. Murphy, Nature 2002, 416, 279-279.
5. S. J. Moss, C. D. Murphy, J. T. G. Hamilton, W. C. McRoberts, D. O'Hagan, C. Schaffrath, D. B. Harper, Chem. Commun. 2000, 2281-2282.
6. C. D. Murphy, S. J. Moss, D. O'Hagan, Appl. Environ. Microbiol. 2001, 67, 4919-4921.
7. C. D. Murphy, D. O'Hagan, C. Schaffrath, Angew. Chem. 2001, 113, 4611-4613; Angew. Chem. Int. Ed. 2001, 40, 4479-4481.
8. C. D. Murphy, D. O'Hagan, C. Schaffrath, Angew. Chem. 2001, 113, 4611-4613; Angew. Chem. Int. Ed. 2001, 40, 4479-4481.
9. J. T. G. Hamilton, C. D. Murphy, M. R. Amin, D. O'Hagan, D. B. Harper, J. Chem. Soc. Perkin Trans. 1 1998, 759-767.
10. Z. Wang, F. A. Quiocho, Biochemistry 1998, 37, 8314-8324.
11. D. Gani, A. W. Johnson, J. Chem. Soc. Perkin Trans. 1 1197-1204.
12. S. J. Moss, PhD thesis. University of Durham, 1999.
13. H. M. Kissman, M. J. Weiss, J. Am Chem. Soc. 1958, 80, 5559-5564.