[Met5]enkephalin-Arg-Gly-Leu-induced antinociception is greatly increased by peptidase inhibitors

European Journal of Pharmacology

Volumn 453, Issue 1, 2002, Pages 53-58

  Kanai, Masayuki ^a   Takahashi, Shigeru ^a   Kosaka, Kenya ^a   Iwao, Kayoko ^a   Kobayashi, Hiroyuki ^a   Oka, Tetsuo ^a  

^a TOKAI UNIVERSITY   (Japan)

Author keywords

Met5 enkephalin Arg Gly Leu; Antinociception; Opioid peptide; Peptidase inhibitor

Indexed keywords

AMASTATIN; CAPTOPRIL; ENZYME INHIBITOR; METENKEPHALIN; METENKEPHALIN[6 ARGININE 7 GLYCINE 8 LEUCINE]; METENKEPHALIN[ARGININE GLYCINE LEUCINE]; PEPTIDASE; PHOSPHORAMIDON; UNCLASSIFIED DRUG; ANALGESIC AGENT; DRUG DERIVATIVE; ENKEPHALIN MET, ARG(6) GLY(7) LEU(8); ENKEPHALIN-MET, ARG(6)-GLY(7)-LEU(8)-; PROTEINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; ENZYME INACTIVATION; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TAIL FLICK TEST; ANIMAL; DOSE RESPONSE; DRUG COMBINATION; DRUG POTENTIATION; METHODOLOGY; PAIN ASSESSMENT; WISTAR RAT;

ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; ENKEPHALIN, METHIONINE; MALE; PAIN MEASUREMENT; PROTEASE INHIBITORS; RATS; RATS, WISTAR;

EID: 0037130954     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02392-0     Document Type: Article

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