The absence of statistical significance in a clinical trial does not mean therapeutic equivalence

Medicina Clinica

Volumn 118, Issue 18, 2002, Pages 701-703

  Argimon, Josep M ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; STEROID; WARFARIN;

ARTICLE; ASTHMA; BLEEDING; CALCULATION; CEREBROVASCULAR ACCIDENT; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; HUMAN; MORTALITY; PHARMACOKINETICS; RECURRENT DISEASE; STATISTICAL ANALYSIS; COMPARATIVE STUDY; CONFIDENCE INTERVAL; STATISTICAL MODEL; STATISTICS;

CLINICAL TRIALS; CONFIDENCE INTERVALS; HUMANS; MODELS, STATISTICAL; STATISTICS; THERAPEUTIC EQUIVALENCY;

EID: 0037129755     PISSN: 00257753     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0025-7753(02)72502-5     Document Type: Article

References (18)

1. Absence of evidence is not evidence of absence
2. A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke
3. Clinical equivalence
4. Therapeutic equivalence: All studies are not created equal
5. Placebo-controlled trials and active-control trials in the evaluation of new treatments. Part 1: Ethical and scientific issues
6. Placebo-controlled trials and active-control trials in the evaluation of new treatments. Part 2: Practical issues and specific cases
7. Trials to assess equivalence: The importance of rigorous methods
8. Similar, the same or just not different: A guide for deciding whether treatments are clinically equivalent
9. Estimación del tamaño de la muestra en la investigación clinica y epidemiológica
10. Randomised, double-blind comparison of reteplase double-bolus administration with streptokinase in acute myocardial infarction: Trial to investigate equivalence
11. An international randomized trial comparing four thrombolytic strategies for acute muyocardial infarction
12. A comparison of continuous infusion of alteplase with double bolus administration for acute myocardial infarction
13. Equivalence trials
14. El intervalo de confianza: Algo más que un valor de significación estadística
15. Claims of equivalence in medical research: Are they supported by the evidence?
16. Ensayos clínicos con medicamentos. Fundamentos básicos, metodología y práctica
17. Practical issues in equivalence trials