A new entry to the stereoselective introduction of an ethynyl group by a radical reaction: Synthesis of the potential antimetabolite 2′-deoxy-2′-C-ethynyluridine

Angewandte Chemie - International Edition

Volumn 41, Issue 24, 2002, Pages 4748-4750

  Sukeda, Makoto ^a   Ichikawa, Satoshi ^a   Matsuda, Akira ^a   Shuto, Satoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Alkynes; C C coupling; Elimination; Nucleosides; Radical reactions

Indexed keywords

IODINE COMPOUNDS; REACTION KINETICS; SYNTHESIS (CHEMICAL);

STEREOSELECTIVITY;

ETHERS;

2' DEOXY 2' C ETHYNYLURIDINE; 2'-DEOXY-2'-C-ETHYNYLURIDINE; ALPHA HYDROXYETHYNYL DERIVATIVE; ANTIMETABOLITE; CHEMICAL COMPOUND; DRUG DERIVATIVE; ETHER DERIVATIVE; ETHYNYL GROUP; ETHYNYLDIMETHYLSILYL ETHER; FLUORIDE; IODINE DERIVATIVE; IODOHYDRIN; TETRABUTYLAMMONIUM FLUORIDE; UNCLASSIFIED DRUG; URIDINE; URIDINE DERIVATIVE;

ARTICLE; ATOM; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; RADICAL REACTION; STEREOCHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ANTIMETABOLITES; MOLECULAR STRUCTURE; STEREOISOMERISM; URIDINE;

EID: 0037122043     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200290037     Document Type: Article

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