Silica-based artificial protease exploiting aldehyde groups as catalytic elements

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 18, 2002, Pages 2557-2560

  Kim, Hyunsook ^a   Paik, Hyesun ^a   Kim, Myoung Soon ^a   Chung, Yeon Sook ^a   Suh, Junghun ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ALDEHYDE; IMMUNOGLOBULIN; INDOLE; PROTEINASE; SILICON DIOXIDE;

ARTICLE; CATALYSIS; COMPLEX FORMATION; ENZYME ANALYSIS; ENZYME SYNTHESIS; GEL; HYDROLYSIS; PROTEIN ANALYSIS; PROTEIN BINDING; SURFACE PROPERTY;

ALDEHYDES; CATALYSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASES; HYDROLYSIS; KINETICS; SILICON DIOXIDE;

EID: 0037119771     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00484-5     Document Type: Article

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20. 0illustrated in Figure 3 may be related to the participation of ionized and neutral forms of aldehyde hydrates. The pH profile, however, reflects ionization of functional groups of the protein substrate as well as the catalyst.