Solid-phase synthesis of 3-alkylamino-1,2,4-triazoles

Organic Letters

Volumn 4, Issue 10, 2002, Pages 1751-1754

  Makara, Gergely M ^a   Ma, Yao ^a   Margarida, Laura ^a  

^a NeoGenesis Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; HYDRAZINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; HYDRAZINES; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; TRIAZOLES;

EID: 0037118346     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol025821i     Document Type: Article

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19. 2COCl (0.125 mmol). The mixture was tumbled overnight at room temperature. The resin was filtered and washed with dichloromethane (3×), 2-propanol (3×), and dichloromethane (3×) to give resin 3.
20. 6 δ 7.58 (d, 2H), 7.15 (d, 2H), 3.93 (s, 3H), 3.08 (d, 2H), 2.88 (m, 1H), 2.00-1.63 (m, 6H), 1.287 (m, 4H), 0.98 (d, 6H), 0.90 (m, 1H).