Enhanced activity of human N-myristoyltransferase by dimethyl sulfoxide and related solvents in the presence of serine/threonine-containing peptide substrates

Biochemical Pharmacology

Volumn 64, Issue 10, 2002, Pages 1461-1467

  Pasha, Mohammed Khysar ^a   Dimmock, Jonathan R ^b   Hollenberg, Morley D ^c   Sharma, Rajendra K ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

Dimethyl sulfoxide; N Myristoyltransferase; Peptide substrates; Regulation

Indexed keywords

AMMONIUM CHLORIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIMETHYL SULFOXIDE; FORMAMIDE DERIVATIVE; GLYCYLALANYLGLUTAMYLPHENYLALANYLSERYLLYSYLTHREONYLALANYLARGINYLARGININE; GLYCYLASPARAGINYLALANYLALANYLALANYLALANYLLYSYLLYSYLARGINYLARGININE; GLYCYLASPARAGINYLALANYLSERYLSERYLISOLEUCYLLYSYLLYSYLLYSINE; GLYCYLSERYLSERYLLYSYLSERYLLYSYLPROLYLLYSYLARGININE; HYDROGEN; HYDROXYL GROUP; MARCKS PROTEIN; PEPTIDE DERIVATIVE; PROTEIN N MYRISTOYLTRANSFERASE; PROTEIN SERINE THREONINE KINASE; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; ATOM; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HYDROGEN BOND; INFRARED RADIATION; INFRARED SPECTROSCOPY; PRIORITY JOURNAL;

ACYLTRANSFERASES; DIMETHYL SULFOXIDE; ENZYME ACTIVATION; ESCHERICHIA COLI; HUMANS; PEPTIDES; SERINE; SOLVENTS; SUBSTRATE SPECIFICITY; THREONINE;

EID: 0037111920     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01412-0     Document Type: Article

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